4493-32-7

Basic information

• Product Name: 1,3-dihydro-1-phenyl-2h-benzimidazole-2-thion
• Synonyms: 1,3-dihydro-1-phenyl-2h-benzimidazole-2-thion;1-Phenyl-2-mercapto benzimidazole;1-phenyl-3H-benzoimidazole-2-thione;1-Phenyl-1H-benzo[d]iMidazol-2-thiol;1,3-Dihydro-1-phenyl-2H-benzimidazole-2-thione;1-phenyl-1H-benzimidazole-2-thiol;2H-Benzimidazole-2-thione, 1,3-dihydro-1-phenyl-;3-phenyl-1H-benzimidazole-2-thione
• CAS NO: 4493-32-7
• Molecular Formula: C₁₃H₁₀N₂S
• Molecular Weight: 226.2969
• Mol File: 4493-32-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 303-304 °C
• Boiling Point: 367.3 °C at 760 mmHg
• Flash Point: 175.9 °C
• Appearance: /
• Density: 1.35 g/cm³
• Vapor Pressure: 1.38E-05mmHg at 25°C
• Refractive Index: 1.758
• PKA: 10.76±0.30(Predicted)
• CAS DataBase Reference: 1,3-dihydro-1-phenyl-2h-benzimidazole-2-thion(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-dihydro-1-phenyl-2h-benzimidazole-2-thion(4493-32-7)
• EPA Substance Registry System: 1,3-dihydro-1-phenyl-2h-benzimidazole-2-thion(4493-32-7)

Safety Data

• Hazardous Substances Data: 4493-32-7(Hazardous Substances Data)

Usage

General Description

1,3-dihydro-1-phenyl-2H-benzimidazole-2-thion is a chemical compound with the molecular formula C13H11N3S. It is a heterocyclic compound that consists of a benzimidazole ring with a phenyl group attached to it. 1,3-dihydro-1-phenyl-2h-benzimidazole-2-thion is known for its diverse range of biological and pharmacological activities, including antifungal, antioxidant, and antitumor properties. It is commonly used in the pharmaceutical industry for drug development and has been studied for its potential therapeutic applications in various diseases. Additionally, its unique chemical structure and properties make it a valuable tool for research and development in the fields of medicinal chemistry and pharmacology.

InChI:InChI=1/C13H10N2S/c16-13-14-11-8-4-5-9-12(11)15(13)10-6-2-1-3-7-10/h1-9H,(H,14,16)

Upstream product

• 534-85-0 N-phenyl-1,2-benzenediamine 
• 134469-07-1 Benzimidazol-2-thiol 
• 98-80-6 phenylboronic acid 
• 119-75-5 2-nitro-N-phenylaniline 
• 53013-42-6 N-phenyl-2-nitrosoaniline 
• 62-53-3 aniline 
• 98-95-3 nitrobenzene 
• 75-15-0 carbon disulfide 

Downstream Products

• 2622-60-8 1-phenyl-1H-benzoimidazole 
• 27185-24-6 benzyl-(1-phenyl-1H-benzoimidazol-2-yl)-amine 
• 4502-98-1 2-(methylthio)-1-phenylbenzimidazole 
• 93730-91-7 dimethyl-[2-(1-phenyl-1H-benzoimidazol-2-ylsulfanyl)-ethyl]-amine 
• 93866-15-0 (1-phenyl-1H-benzoimidazol-2-ylsulfanyl)-acetic acid 
• 93020-46-3 2-(allylthio)-1-phenylbenzimidazole 
• 100546-20-1 thiobenzoic acid S-(1-phenyl-1H-benzoimidazol-2-yl) ester 
• 97081-35-1 2-(benzylthio)-1-phenylbenzimidazole 
• 3908-91-6 2-methanesulfonyl-1-phenyl-1H-benzoimidazole 
• 95815-88-6 1-phenyl-2-(1-phenyl-1H-benzoimidazol-2-ylsulfanyl)-ethanone 

Relevant articles and documents

N, O-Bidentate ligand-tunable copper(II) complexes as a catalyst for Chan-Lam coupling reactions of arylboronic acids with 1 H-imidazole derivatives

An efficient procedure for Chan-Lam coupling reactions of arylboronic acids with 1H-imidazole derivatives using N,O-bidentate ligand-tunable copper(ii) complexes as a catalyst under base-free conditions has been developed. This protocol features mild reac

Process for making 2-mercapto benzimidazoles in the presence of a water-insoluble alkanol

A process is provided for making benzimidazoles having the formula STR1 wherein Y is oxygen, sulfur or --NH; R1 is hydrogen, C1 -C12 alkyl, C5 -C6 cycloalkyl, C6 -C10 aryl, C7 -C9 aralkyl or C7 -C9 alkaryl; R2 is hydrogen, C1 -C4 alkyl, C1 -C4 alkoxy or halogen; and n is 1 or 2; comprising reacting a compound having the formula ZYCN, wherein Z is an alkali metal or ammonium moiety and Y has the meanings above; with a compound having the formula STR2 wherein R1, R2 and n have the meanings above, in the presence of a C4 -C10 alkanol and, except when Z is NH4, in the presence of an acid.

Compounds with antiulcer and antisecretory activity. I. 3-Aryl-benzimidazolin-2-ones and -thiones

-