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Alpha-methyltyrosine methyl ester (AMTE) is a synthetic chemical compound that serves as a selective and potent inhibitor of the enzyme tyrosine hydroxylase, which plays a crucial role in the biosynthesis of the neurotransmitters dopamine, norepinephrine, and epinephrine. By inhibiting this enzyme, AMTE effectively reduces the production of these neurotransmitters, making it a valuable research tool for studying the effects of altered dopaminergic and adrenergic signaling in various biological systems. Its chemical structure is characterized by a methyl group attached to the alpha carbon of the tyrosine molecule, with a methyl ester group at the carboxylic acid end, which contributes to its selectivity and potency as an inhibitor. AMTE is primarily used in scientific research to investigate the role of catecholamines in physiological and pathological processes, and its potential applications in the development of therapeutic strategies for neurodegenerative diseases and other conditions related to catecholamine dysregulation.

4502-13-0

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4502-13-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4502-13-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,5,0 and 2 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 4502-13:
(6*4)+(5*5)+(4*0)+(3*2)+(2*1)+(1*3)=60
60 % 10 = 0
So 4502-13-0 is a valid CAS Registry Number.

4502-13-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl 2-((4-hydroxyphenyl)methyl)-2-aminopropionate

1.2 Other means of identification

Product number -
Other names α-methyl-p-tyrosine methyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4502-13-0 SDS

4502-13-0Relevant academic research and scientific papers

Synthesis and in vitro evaluation of 18F labeled tyrosine derivatives as potential positron emission tomography (PET) imaging agents

Wang, Limin,Qu, Wenchao,Lieberman, Brian,Ploessl, Karl,Kung, Hank F.

scheme or table, p. 3482 - 3485 (2010/08/22)

Three new 18F labeled fluoroalkyl tyrosine derivatives, O-(2-[18F]fluoroethyl)-α-methyltyrosine (FEMT, [ 18F]2), O-(2-[18F]fluoroethyl)-2-l-azatyrosine (FEAT, [18F]3), O-(2-[18F]fluoroethyl

BENZAMIDINE DERIVATIVES SUBSTITUTED BY AMINO ACID AND HYDROXY ACID DERIVATIVES AND THEIR USE AS ANTI-COAGULANTS

-

, (2008/06/13)

This invention is directed to benzamidine derivatives substituted by amino acid and hydroxy acid derivatives which are useful as anti-coagulants. This invention is also directed to pharmaceutical compositions containing the compounds of the invention, and methods of using the compounds to treat disease-states characterized by thrombotic activity.

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