450353-87-4Relevant academic research and scientific papers
Discovery of 2-iminobenzimidazoles as a new class of trypanothione reductase inhibitor by high-throughput screening
Holloway, Georgina A.,Baell, Jonathan B.,Fairlamb, Alan H.,Novello, Patrizia M.,Parisot, John P.,Richardson, John,Watson, Keith G.,Street, Ian P.
, p. 1422 - 1427 (2007)
A high-throughput screening campaign of a library of 100,000 lead-like compounds identified 2-iminobenzimidazoles as a novel class of trypanothione reductase inhibitors. These 2-iminobenzimidazoles display potent trypanocidal activity against Trypanosoma
