4512-98-5Relevant articles and documents
Stereoselective Synthesis of Z-Vinyl Selenides Through the Reaction of Sodium Selenide with Organic Halides and Alkynes
Pistoia, Renan P.,Back, Davi F.,Zeni, Gilson
supporting information, p. 3794 - 3798 (2019/06/21)
A practical synthetic approach to the stereoselective synthesis of Z-vinyl selenides is described through the reaction of sodium selenide with organic halides, followed by the addition to alkynes. The reaction conditions were also successfully applied to
Efficient synthesis of polymethoxyselenoflavones via regioselective direct C-H arylation of selenochromones
Yang, Woo-Ram,Choi, Yong-Sung,Jeong, Jin-Hyun
, p. 3074 - 3083 (2017/04/10)
Substantial research has suggested that the configuration and the total number of functional groups on flavones influence their bioactivity. To investigate the changes in the biological activities of selenoflavones in relationship to structural changes, the development of a generally applicable synthetic method was a key. Until now, an efficient pathway for palladium-catalyzed direct arylation with the selenocyclic enone systems is not known in the literature. We herein introduce a simple direct C-H arylation of two difficult coupling partners, selenochromones and electron-rich aryl bromide, affording diverse polymethoxyselenoflavones with great efficiency and high selectivity.
