4519-33-9

Basic information

• Product Name: PHENYL N,N,N',N'-TETRAETHYLPHOSPHORODIAMIDATE
• Synonyms: PHENYL N,N,N',N'-TETRAETHYLPHOSPHORODIAMIDATE
• CAS NO: 4519-33-9
• Molecular Formula: C₁₄H₂₅N₂O₂P
• Molecular Weight: 284.334261
• Mol File: 4519-33-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 351.9°Cat760mmHg
• Flash Point: 166.6°C
• Appearance: /
• Density: 1.062g/cm³
• CAS DataBase Reference: PHENYL N,N,N',N'-TETRAETHYLPHOSPHORODIAMIDATE(CAS DataBase Reference)
• NIST Chemistry Reference: PHENYL N,N,N',N'-TETRAETHYLPHOSPHORODIAMIDATE(4519-33-9)
• EPA Substance Registry System: PHENYL N,N,N',N'-TETRAETHYLPHOSPHORODIAMIDATE(4519-33-9)

Safety Data

• Hazardous Substances Data: 4519-33-9(Hazardous Substances Data)

Upstream product

• 1794-24-7 tetraethyldiamidochlorophosphate 
• 108-95-2 phenol 

Downstream Products

• 16604-63-0 o-tolyl N,N,N',N'‐tetraethylphosphorodiamidate 
• 644-08-6 4-Methylbiphenyl 

Relevant articles and documents

The Tetraethylphosphorodiamidate (OP(O)(NEt2)2) Directed Metalation Group (DMG). Directed ortho and Lateral Metalation and the Phospha Anionic Fries Rearrangement

We report on the tetraethylphosphorodiamidate (-OP(O)(NEt2)2) group as an effective directed metalation group (DMG). Lithiation-electrophile quench of 1 provides a general synthesis of ortho-substituted aryl and naphthyl phosphorodiamidates 4-8. We also describe the phospha anionic ortho-Fries (AoF) rearrangement of the phosphorodiamidates 1a,1ba2 or 3 and its vinylogous counterpart to the ortho-tolyl phosphorodiamidates 5ba 13. Intermolecular competition experiments demonstrate the approximately equal DMG strength of the-OP(O)(NEt2)2 and the most powerful OCONEt2 groups.