452082-46-1

Upstream product

• 112-72-1 1-Tetradecanol 
• 86-93-1 1-Phenyl-1H-tetrazole-5-thiol 
• 112-71-0 1-Bromotetradecane 

Downstream Products

• 152386-86-2 (2R,3R,4E)-1,2-O-pentylidene-3-(4-methoxybenzyl)-4-octadecen-1,2,3-triol 
• 792912-97-1 2,4-bis-(tert-butyldimethylsilanyloxy)-3-[(R)-3-methyl-5-(tetradecyliden)tetrahydropyran-2-(R)-yl]-5-phenylpyridine 

Relevant academic research and scientific papers

Toward the synthesis of the hypoxia selective anticancer agent BE-43547 A2

A short and enantioselective synthesis of the 19-epi-BE-43547 A2 chiral framework has been achieved in a high yield. The challenging key C15 tertiary stereocenter was derived from d-glucose. The synthetic strategy involves a Julia-Kocienski olefination to install the lipophilic side chain. An efficient protocol for Z to E isomerization of olefin was developed using a novel UV flow reactor. In addition, an unprecedented oxygen mediated hydroboration and the Krapcho decarboxylation of β-keto lactone were observed. This journal is

Synthetic epoxy-mycolic acids

We report the synthesis of single enantiomers of epoxy-mycolic acids containing an α-methyl-trans-alkene or a cis-cyclopropane with structures that match those of major isomers of such molecules present in complex mixtures in Mycobacteria such as Mycobact

A formal synthesis of 3-O-(4-methoxybenzyl)-azidosphingosine by a modified Julia olefination

The stereoselective construction of the D-erythro-azidosphingosine characteristic trans double bond was accomplished by condensation between tetradecanal and a heterocyclic sulfone derived from diethyl-D-tartrate, following the Kocienski modification of the Julia olefination.