452304-59-5

Usage

Uses

Used in Pharmaceutical Industry:
(1R,2R)-2-(Diphenylphosphino)-1-aminocyclohexane, min. 97% is used as a chiral ligand in the synthesis of pharmaceuticals for its ability to selectively form enantiomerically pure products, which is essential for the development of effective and safe drugs.
Used in Agrochemical Industry:
In the agrochemical industry, (1R,2R)-2-(Diphenylphosphino)-1-aminocyclohexane, min. 97% is utilized as a chiral ligand in the synthesis of agrochemicals, ensuring the production of enantiomerically pure compounds to enhance the effectiveness and reduce the environmental impact of these chemicals.
Used in Fine Chemicals Synthesis:
(1R,2R)-2-(Diphenylphosphino)-1-aminocyclohexane, min. 97% is employed as a chiral ligand in the synthesis of fine chemicals, contributing to the creation of high-quality specialty chemicals with specific chiral properties for various applications.
Used in Material Development:
(1R,2R)-2-(Diphenylphosphino)-1-aminocyclohexane, min. 97% is used as a key component in the development of new materials, where its chiral properties are leveraged to create materials with unique characteristics and improved performance.
Used in Academic Research:
In academic research, (1R,2R)-2-(Diphenylphosphino)-1-aminocyclohexane, min. 97% is used as a fundamental component in the preparation of chiral catalysts, driving advancements in catalytic processes and the discovery of new catalytic systems.

Upstream product

• 286-20-4 cyclohexane-1,2-epoxide 
• 2562-37-0 1-nitrocyclohexene 
• 829-85-6 diphenylphosphane 
• 286-18-0 7-azabicyclo[4.1.0]heptane 

Downstream Products

• 1023287-38-8 C₃₆H₄₀N₃OPS 
• 1264974-07-3 C₂₅H₂₈NO₃P 
• 1264974-10-8 C₂₉H₂₈NO₃P 
• 1264974-04-0 C₂₄H₂₆NO₃P 
• 1314102-49-2 (2R,3R,4S,5S,6R)-2-(acetoxymethyl)-6-(3-((1R,2R)-2-(diphenylphosphino)cyclohexyl)thioureido)-tetrahydro-2H-pyran-3,4,5-triyl triacetate 
• 1314102-47-0 (2R,3S,4S,5R,6R)-2-(acetoxymethyl)-6-(3-((1R,2R)-2-(diphenylphosphino)cyclohexyl)thioureido)-tetrahydro-2H-pyran-3,4,5-triyl triacetate 

Relevant academic research and scientific papers

Design and development of cyclohexane-based P,N-ligands for transition metal catalysis

(Matrix presented) R1 = H, Pht R2 = Ph, Cy A new class of cyclohexane-based P,N-ligands is readily obtained through aziridine ring opening with suitable phosphorus nucleophiles under acidic conditions. tran-1-Amino-2-diphenylphosphin

Palladium-catalyzed asymmetric 1,4-addition of diarylphosphines to nitroalkenes for the synthesis of chiral P,N-compounds

A highly stereoselective asymmetric 1,4-addition of diarylphosphines to nitroalkenes catalyzed by a bis(phosphine) pincer-palladium complex has been developed for the synthesis of chiral P,N compounds with good to excellent enantioselectivities (up to 94% ee) under mild conditions. Copyright

Synthesis of chiral aminophosphines from chiral aminoalcohols via cyclic sulfamidates

(Chemical Equation Presented) Protic aminophosphines with multiple chiral centers were synthesized in good yields and high purity by the nucleophilic ring-opening of N-protected cyclic sulfamidates with metal phosphides, followed by hydrolysis and deprote

Cooperative, highly enantioselective phosphinothiourea catalysis of imine - Allene [3 + 2] cycloadditions

A new family of phosphinthiourea catalysts was developed for the highly enantioselective synthesis of 2-aryl-2,5-hydropyrroles via a [3 + 2] cycloaddition of an electron-deficient allene with aryl and heteroaryl diphenylphosphinoylimines. The presence of