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(1R,2R)-2-(Diphenylphosphino)-1-aminocyclohexane, min. 97% is a chiral ligand chemical compound, typically appearing as a white to off-white solid with a minimum purity of 97%. It is widely recognized for its role in asymmetric synthesis, where it imparts chirality to metal catalysts, facilitating the selective formation of enantiomerically pure products. (1R,2R)-2-(Diphenylphosphino)-1-aminocyclohexane, min. 97% is a crucial reagent in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals, as well as in the development of new materials and academic research for the preparation of chiral catalysts.

452304-59-5

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452304-59-5 Usage

Uses

Used in Pharmaceutical Industry:
(1R,2R)-2-(Diphenylphosphino)-1-aminocyclohexane, min. 97% is used as a chiral ligand in the synthesis of pharmaceuticals for its ability to selectively form enantiomerically pure products, which is essential for the development of effective and safe drugs.
Used in Agrochemical Industry:
In the agrochemical industry, (1R,2R)-2-(Diphenylphosphino)-1-aminocyclohexane, min. 97% is utilized as a chiral ligand in the synthesis of agrochemicals, ensuring the production of enantiomerically pure compounds to enhance the effectiveness and reduce the environmental impact of these chemicals.
Used in Fine Chemicals Synthesis:
(1R,2R)-2-(Diphenylphosphino)-1-aminocyclohexane, min. 97% is employed as a chiral ligand in the synthesis of fine chemicals, contributing to the creation of high-quality specialty chemicals with specific chiral properties for various applications.
Used in Material Development:
(1R,2R)-2-(Diphenylphosphino)-1-aminocyclohexane, min. 97% is used as a key component in the development of new materials, where its chiral properties are leveraged to create materials with unique characteristics and improved performance.
Used in Academic Research:
In academic research, (1R,2R)-2-(Diphenylphosphino)-1-aminocyclohexane, min. 97% is used as a fundamental component in the preparation of chiral catalysts, driving advancements in catalytic processes and the discovery of new catalytic systems.

Check Digit Verification of cas no

The CAS Registry Mumber 452304-59-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,5,2,3,0 and 4 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 452304-59:
(8*4)+(7*5)+(6*2)+(5*3)+(4*0)+(3*4)+(2*5)+(1*9)=125
125 % 10 = 5
So 452304-59-5 is a valid CAS Registry Number.

452304-59-5 Well-known Company Product Price

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  • Alfa Aesar

  • (H60084)  (1R,2R)-(-)-2-(Diphenylphosphino)cyclohexylamine, 97+%   

  • 452304-59-5

  • 250mg

  • 978.0CNY

  • Detail
  • Alfa Aesar

  • (H60084)  (1R,2R)-(-)-2-(Diphenylphosphino)cyclohexylamine, 97+%   

  • 452304-59-5

  • 1g

  • 3020.0CNY

  • Detail
  • Aldrich

  • (748315)  (1R,2R)-2-(Diphenylphosphino)cyclohexylamine  95%

  • 452304-59-5

  • 748315-500MG

  • 2,478.06CNY

  • Detail

452304-59-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (1R,2R)-2-diphenylphosphanylcyclohexan-1-amine

1.2 Other means of identification

Product number -
Other names (1R,2R)-2-(Diphenylphosphino)cyclohexanamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:452304-59-5 SDS

452304-59-5Relevant academic research and scientific papers

Design and development of cyclohexane-based P,N-ligands for transition metal catalysis

Caiazzo, Aldo,Dalili, Shadi,Yudin, Andrei K.

, p. 2597 - 2600 (2002)

(Matrix presented) R1 = H, Pht R2 = Ph, Cy A new class of cyclohexane-based P,N-ligands is readily obtained through aziridine ring opening with suitable phosphorus nucleophiles under acidic conditions. tran-1-Amino-2-diphenylphosphin

Palladium-catalyzed asymmetric 1,4-addition of diarylphosphines to nitroalkenes for the synthesis of chiral P,N-compounds

Feng, Jian-Jun,Huang, Miao,Lin, Zi-Qi,Duan, Wei-Liang

supporting information, p. 3122 - 3126 (2013/01/15)

A highly stereoselective asymmetric 1,4-addition of diarylphosphines to nitroalkenes catalyzed by a bis(phosphine) pincer-palladium complex has been developed for the synthesis of chiral P,N compounds with good to excellent enantioselectivities (up to 94% ee) under mild conditions. Copyright

Synthesis of chiral aminophosphines from chiral aminoalcohols via cyclic sulfamidates

Guo, Rongwei,Lu, Shuiming,Chen, Xuanhua,Tsang, Chi-Wing,Jia, Wenli,Sui-Seng, Christine,Amoroso, Dino,Abdur-Rashid, Kamaluddin

supporting information; experimental part, p. 937 - 940 (2010/05/02)

(Chemical Equation Presented) Protic aminophosphines with multiple chiral centers were synthesized in good yields and high purity by the nucleophilic ring-opening of N-protected cyclic sulfamidates with metal phosphides, followed by hydrolysis and deprote

Cooperative, highly enantioselective phosphinothiourea catalysis of imine - Allene [3 + 2] cycloadditions

Fang, Yuan-Qing,Jacobsen, Eric N.

, p. 5660 - 5661 (2008/12/21)

A new family of phosphinthiourea catalysts was developed for the highly enantioselective synthesis of 2-aryl-2,5-hydropyrroles via a [3 + 2] cycloaddition of an electron-deficient allene with aryl and heteroaryl diphenylphosphinoylimines. The presence of

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