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Z-Pro-Gly-Gly-OEt is a chemical compound that features a protected dipeptide structure, characterized by the presence of a benzyloxycarbonyl (Cbz) protecting group on the amino terminus of the peptide sequence. This dipeptide is composed of the amino acid proline (Pro) followed by two glycine residues (Gly-Gly), and it is capped with an ethyl ester (OEt) group. Its design allows for selective deprotection and manipulation during peptide synthesis, making it a valuable building block in the preparation of more complex peptides for various applications in organic synthesis and peptide chemistry.

4526-86-7

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4526-86-7 Usage

Uses

Used in Organic Synthesis:
Z-Pro-Gly-Gly-OEt is used as a building block for the synthesis of more complex organic compounds, leveraging its protected dipeptide structure to facilitate selective reactions and the formation of desired molecular architectures.
Used in Peptide Chemistry:
In peptide chemistry, Z-Pro-Gly-Gly-OEt serves as a key component in the assembly of larger peptide sequences. Its protected structure ensures that the peptide bonds can be formed selectively, which is crucial for the synthesis of peptides with specific biological activities or properties.
Used in Pharmaceutical Development:
Z-Pro-Gly-Gly-OEt may be utilized in the development of pharmaceuticals, particularly in the creation of peptide-based drugs. Its protected nature allows for the controlled synthesis of peptides with potential therapeutic applications, such as antibiotics, vaccines, or treatments for various diseases.
Used in Research and Development:
In research settings, Z-Pro-Gly-Gly-OEt can be employed as a model compound to study the synthesis, properties, and behavior of protected peptides. This can contribute to the advancement of understanding in peptide chemistry and the development of new synthetic strategies and techniques.
Used in Biochemical Applications:
Z-Pro-Gly-Gly-OEt may also find use in biochemical applications, such as in the study of protein folding, stability, and interactions. Its protected structure can provide insights into the role of protecting groups in influencing peptide conformation and function.

Check Digit Verification of cas no

The CAS Registry Mumber 4526-86-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,5,2 and 6 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4526-86:
(6*4)+(5*5)+(4*2)+(3*6)+(2*8)+(1*6)=97
97 % 10 = 7
So 4526-86-7 is a valid CAS Registry Number.

4526-86-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Z-Pro-Gly-Gly-OEt

1.2 Other means of identification

Product number -
Other names ethyl N-benzyloxycarbonylprolinylglycylglycinate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:4526-86-7 SDS

4526-86-7Relevant articles and documents

Process for synthesizing active esters of carboxylic acids

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, (2008/06/13)

The invention relates to a new process for preparing active esters or carboxylic acids, which consists in reacting a carboxylic acid, in the presence of an agent for binding hydrohalic acid, with a carbonate of formula: STR1 in which R1 denotes either a radical of formula STR2 in which R3 and R4, which may be identical or different, are not hydrogen atoms and denote organic radicals which may be substituted or unsubstituted and saturated or unsaturated, and may be or may not be bound to a polymer, and which can be joined together to form a hetero-cyclic system with the nitrogen atom, or a substituted or unsubstituted aryl radical which may or may not be bound to a polymer, R2 denotes a hydrogen atom, an aliphatic or cycloaliphatic radical which may be substituted or unsubstituted and saturated or unsaturated, or a substituted or unsubstituted aromatic radical, and X denotes a halogen atom. This process is especially useful for the synthesis of active esters of N-protected amino acids. The invention also relates to the new carbonates described above and the method of producing them, which consists in reacting an alpha-halogenated chloroformate of formula: with an alcohol of formula R1 OH in an inert solvent medium of the presence of an organic or inorganic base.

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