452972-09-7 Usage
Chemical Properties
white to light yellow crystal powde
Uses
Reactant for preparation of:? ;Thienylpyridyl garlands via cross-coupling with heteroaryl halides1? ;Arenes via nickel-catalyzed cross-coupling with potassium aryl- and heteroaryl trifluoroborates2? ;Meso-substituted ABCD-type porphyrins by functionalization reactions3? ;Analogs of (acetylamino)(dimethylpyrazol)(pyridyl)pyrimidines as A2A adenosine receptor antagonists for the treatment of Parkinson′s disease4? ;5-hydroxy-1,3,2-dioxaborolan-4-ones boronate-amine complexes via heterocyclization with α-oxocarboxylic acids followed by subsequent complexation5&
Check Digit Verification of cas no
The CAS Registry Mumber 452972-09-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,5,2,9,7 and 2 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 452972-09:
(8*4)+(7*5)+(6*2)+(5*9)+(4*7)+(3*2)+(2*0)+(1*9)=167
167 % 10 = 7
So 452972-09-7 is a valid CAS Registry Number.
InChI:InChI=1/C5H5BBrNO2/c7-5-1-4(6(9)10)2-8-3-5/h1-3,9-10H
452972-09-7Relevant articles and documents
Pyrrolopyrimidines and Pyrrolopyridines
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Page/Page column 50, (2009/07/25)
Compounds of formula I in free or salt or solvate form, wherein X, T1, T3 and T4 have the meanings as indicated in the specification, are useful for treating diseases mediated by the ALK-5 and/or ALK-4 receptor. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
New shelf-stable halo- and alkoxy-substituted pyridylboronic acids and their suzuki cross-coupling reactions to yield heteroarylpyridines
Parry, Paul R.,Bryce, Martin R.,Tarbit, Brian
, p. 1035 - 1038 (2007/10/03)
New shelf-stable pyridylboronic acids have been synthesized: bromine-lithium exchange followed by reaction with triisopropylborate (TIPB) yielded 2-fluoro-5-pyridylboronic acid (4), 3-bromo-5-pyridylboronic acid (5) and 2-ethoxy-5-pyridylboronic acid (6);