452972-14-4 Usage
Description
2-Fluoropyridine-3-boronic acid pinacol ester is an organic compound that exists as a white to light yellow solid. It is a derivative of pyridine with a fluorine atom at the 2nd position and a boronic acid pinacol ester group at the 3rd position. 2-FLUOROPYRIDINE-3-BORONIC ACID PINACOL ESTER is known for its unique chemical properties and potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
2-Fluoropyridine-3-boronic acid pinacol ester is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows for the development of new drugs with potential applications in treating different diseases.
Used in Chemical Research:
In the field of chemical research, 2-Fluoropyridine-3-boronic acid pinacol ester serves as a valuable building block for the creation of novel organic molecules. Its reactivity and structural properties make it a useful tool for exploring new chemical reactions and developing innovative synthetic pathways.
Used in Material Science:
2-Fluoropyridine-3-boronic acid pinacol ester can be utilized in the development of new materials with specific properties. Its incorporation into polymers or other materials can lead to enhanced performance characteristics, such as improved stability, reactivity, or selectivity.
Used in Agrochemical Industry:
2-FLUOROPYRIDINE-3-BORONIC ACID PINACOL ESTER can also be employed in the agrochemical industry for the development of new pesticides or herbicides. Its unique chemical properties may contribute to the creation of more effective and environmentally friendly products for agricultural use.
Check Digit Verification of cas no
The CAS Registry Mumber 452972-14-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,5,2,9,7 and 2 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 452972-14:
(8*4)+(7*5)+(6*2)+(5*9)+(4*7)+(3*2)+(2*1)+(1*4)=164
164 % 10 = 4
So 452972-14-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H15BFNO2/c1-10(2)11(3,4)16-12(15-10)8-6-5-7-14-9(8)13/h5-7H,1-4H3
452972-14-4Relevant articles and documents
Protein kinase inhibitor and its composition and use thereof
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Paragraph 0171-0173, (2017/08/02)
The invention relates to compounds as shown in the general formula (I), pharmaceutical compositions containing the compounds, a method for treating diseases and disease symptoms related to abnormal activity of protein kinase by using the compounds, and medicinal use of the compounds.
Fluorine-controlled C-H borylation of arenes catalyzed by a PSiN-pincer platinum complex
Takaya, Jun,Ito, Shisei,Nomoto, Hironori,Saito, Narumasa,Kirai, Naohiro,Iwasawa, Nobuharu
supporting information, p. 17662 - 17665 (2015/12/18)
An efficient, regioselective synthesis of fluorine-substituted arylboronic esters was achieved through fluorine-controlled C-H borylation of arenes with diboron catalyzed by a PSiN-platinum complex. The promising utility of the PSiN-platinum catalyst and its unique regioselectivity were demonstrated for the first time, which would complement the well-developed Ir-catalyzed C-H borylation.
A catalytic borylation/dehalogenation route to o -fluoro arylboronates
Jayasundara, Chathurika R. K.,Unold, Jason M.,Oppenheimer, Jossian,Smith, Milton R.,Maleczka, Robert E.
supporting information, p. 6072 - 6075 (2015/01/09)
A two-step Ir-catalyzed borylation/Pd-catalyzed dehalogenation sequence allows for the net synthesis of fluoroarenes where the boronic ester is ortho to fluorine. Key elements of this approach include the use of a halogen para to the fluorine to block meta Ir-catalyzed borylation and the chemoselective Pd-catalyzed dehalogenation by KF activated polymethylhydrosiloxane (PMHS).