4533-18-0Relevant academic research and scientific papers
RELATIONSHIP BETWEEN THE STRUCTURES OF THE MOLECULES OF INDOLIZINE AND AZAINDOLIZINES AND THE ABILITY OF THESE MOLECULES TO UNDERGO REARRANGEMENT
Aslanov, L. A.,Tafeenko, V. A.,Paseshnichenko, K. A.,Bundel', Yu. G.,Gromov, S. P.,Gerasimov, B. G.
, p. 427 - 434 (1983)
In a continuation of systematic studies of the phenomenon of the isomerizational recyclization of heteroaromatic compounds, the crystal and molecular structure of 2-phenyl-3-acetyl-6-nitroindolizine, 3-phenyl-6-nitroimidazopyridine, and 2-phenyl6-nitroimidazopyridine has been determined by x-ray structural analysis.Comparison of the results of the present work with previously published data shows that when there is a "polyene" chain C8-C6-...C1 or C8-C6-...N1 in the molecules of derivatives of indolizine or imidazopyridine,, respectively, they have the ability to undergo rearrangement, but the realization of this ability depends, in particular, on the steric hindrance in the molecules.
A multi pathway coupled domino strategy: I2/ TBHP-promoted synthesis of imidazopyridines and thiazoles via sp3, sp2 and sp C-H functionalization
Feng, Lei,Li, Shichen,Ma, Chen,Wang, Xinfeng,Wang, Yishou,Yao, Yiming
, p. 5919 - 5927 (2022/03/31)
I2/TBHP-promoted, one-pot, multi pathway synthesis of imidazopyridines and thiazoles has been achieved through readily available ethylarenes, ethylenearenes and ethynearenes. I2/TBHP as an initiator and oxidant is used to realize the C-H functionalization of this domino reaction. Simple and available starting materials, wide range of functional group tolerance, high potential for drug activity of the products and application in production are the advantageous features of this method.
Design and Synthesis of Imidazo[1,2-a]pyridines with Carboxamide Group Substitution and In silico Evaluation of their Interaction with a LuxR-type Quorum Sensing Receptor
Reynoso Lara, Juan Emmanuel,Salgado-Zamora, Héctor,Bazin, Marc-Antoine,Campos-Aldrete, María Elena,Marchand, Pascal
, p. 1101 - 1111 (2018/03/29)
Quorum sensing, an important process of bacterial communication, is involved in the development of complex behavior and expression of virulence factors that become important due to its key role in infection process. In this manuscript, docking studies wer
A copper-catalyzed multi-component reaction accessing fused imidazo-heterocycles via C-H functionalization
Kumar, G. Santosh,Ragini, S. Pushpa,Kumar, A. Sanjeeva,Meshram
, p. 51576 - 51580 (2015/06/25)
An efficient synthesis of fused imidazo-heterocycles is described using Cu(OTf)2 in [bmim]BF4 by the multi-component reaction of pyridin-2(1H)-one or thiazol/benzo[d]thiazol-2(3H)-ones with O-tosylhydroxyl amine and acetophenones under microwave irradiation. The present method is very rapid and the product formation occurs via a C-H functionalization/tandem addition-cyclization process. The ionic liquid containing copper triflate is recovered and reused four times.
Gold-catalyzed redox synthesis of imidazo[1,2-a]pyridines using pyridine N-oxide and alkynes
Talbot, Eric P. A.,Richardson, Melodie,McKenna, Jeffrey M.,Toste, F. Dean
, p. 687 - 691 (2014/04/03)
A mild, catalytic, atom economical synthesis of imidazo[1,2-a]pyridines has been developed: catalytic dichloro(2-pyridinecarboxylato)gold [PicAuCl 2] in the presence of an acid produces a range of imidazo[1,2-a]pyridines in good yields starting
