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Usage

Uses

Used in Animal Feed Production:
Choline chloride is used as a nutritional supplement in animal feed for its role in the metabolism of fats and the development and function of the nervous system, contributing to the overall health and well-being of animals.
Used in Human Dietary Supplements:
As a dietary supplement for humans, choline chloride supports cognitive function and liver health, making it a popular ingredient in health products aimed at enhancing brain and liver function.
Used in Chemical Synthesis:
Choline chloride serves as a precursor for the synthesis of various chemical compounds, highlighting its utility in the chemical industry for the production of a range of products.
Used in Plant Fertilizers:
In agriculture, choline chloride is used as a component in plant fertilizers to promote plant growth and development, leveraging its role in nutrient metabolism.
Used in Road Maintenance:
As a dust-control agent in road maintenance, choline chloride helps to reduce dust emissions and improve air quality around construction sites and roads.
Used in Pharmaceutical Industry:
Choline chloride has potential applications in the pharmaceutical industry, likely due to its role in bodily metabolism and its potential interactions with biological systems, although specific uses are not detailed in the provided materials.
Used in Cosmetic Industry:
Similarly, in the cosmetic industry, choline chloride may be utilized for its effects on skin health or as an ingredient in formulations, although the exact applications are not specified in the provided materials.

Upstream product

• 1072-45-3 N-ethylaziridine 
• 859798-08-6 ethyl-chloro-(2-chloro-ethyl)-amine 
• 110-73-6 2-(Ethylamino)ethanol 
• 7647-01-0 hydrogenchloride 

Downstream Products

• 100141-58-0 ethyl-(2-chloro-ethyl)-carbamic acid benzyl ester 
• 28346-19-2 Benzilsaeure-<2-aethylamino-aethylester> 
• 111-37-5 N-methyl-N'-ethylethane-1,2-diamine 
• 96027-74-6 Desethylamiodarone hydrochloride 

Relevant academic research and scientific papers

Synthesis and structure-activity relationships of 4-amino-5-chloro-N-(1,4- dialkylhexahydro-1,4-diazepin-6-yl)-2-methoxybenzamide derivatives, novel and potent serotonin 5-HT3 and dopamine D2 receptors dual antagonist

In search of a dopamine D2 and serotonin 5-HT3 receptors dual antagonist as a potential broad antiemetic agent, a number of benzamides were prepared from 4-amino-5-chloro-2-methoxybenzoic acid derivatives and 6-amino-1,4-dialkylhexahydro-1,4-diazepines and evaluated for their binding affinity for the dopamine D2 and the serotonin 5-HT3 receptors using rat brain synaptic and rat cortical membranes, respectively. From the results of both in vitro receptor binding and in vivo biological assays for the dopamine D2 receptor, 1-ethyl-4-methylhexahydro-1,4- diazepine ring was selected as an optimum amine moiety. Introduction of one methyl group on the nitrogen atom at the 4-position and/or modification of the substituent at the 5-position of the 4-amino-5-chloro-2-methoxybenzoyl moiety caused a marked increase in the dopamine D2 receptor binding affinity along with a potent 5-HT3 receptor binding affinity. Among the compounds, 5-chloro-N-(1-ethyl-4-methylhexahydro-1,4-diazepin-6-yl)-2-methoxy-4- methylaminobenzamide (82), 5-bromo (110), and 5-iodo (112) analogues exhibited a much higher affinity for the dopamine D2 receptor than that of metoclopramide (IC50=17.5-61.0 nM vs. 483 nM). In particular, 82 showed a potent antagonistic activity for both receptors in vivo tests. Optical resolution of the racemate 82 brought about a dramatic change in the pharmacological profile with the (R)-enantiomer exhibiting a strong affinity for both the dopamine D2 and the 5-HT3 receptors, while the corresponding (S)-enantiomer had a potent and selective serotonin 5-HT 3 receptor binding affinity.

A novel series of N-(hexahydro-1,4-diazepin-6-yl) and N-(hexahydroazepin-3-yl)benzamides with high affinity for 5-HT3 and dopamine D2 receptors

A novel series of benzamides with a hexahydro-1,4-diazepine or hexahydroazepine ring in the amine moiety were prepared, and their binding affinities for 5-HT3 and dopamine 4 receptors were evaluated. The R isomer of the 1-ethyl-4-methylhexahydro-1,4-diazepinylbenzamide (R)-22 had potent affinity for both receptors. The R-enantiomer of the corresponding 1-ethylhexahydroazepinylbenzamide 28 showed potent affinity for dopamine D2 receptors with reduced affinity for 5-HT3 receptors, while the S isomer was found to be a potent and selective 5-HT3 receptor antagonist.

Novel N-(alkyl)-N-(2-haloethyl)-aminomethylphosphonic acids, a method for the preparation thereof and their use in the preparation of starch ether derivatives

Starch ether derivatives are prepared by reacting a starch base with N-(2-haloethyl)iminobis(methylene)diphosphonic acid or with a N-(alkyl)-N-(2-haloethyl)aminomethylphosphonic acid. The derivatives contain aminophosphonic acid groups (or their salts) as