4540-33-4

Basic information

• Product Name: Piperidinium acetate
• Synonyms: PIPERIDINIUM ACETATE;piperidiniumacetate(ep);piperidin-1-iuM;Piperidin-1-iuM acetate;PiperidiniuM acetate, 98%+
• CAS NO: 4540-33-4
• Molecular Formula: C₂H₃O₂*C₅H₁₂N
• Molecular Weight: 145.2
• EINECS: 224-890-7
• Product Categories: Fine Chemical Catalysts
• Mol File: 4540-33-4.mol
• Article Data: 15

Chemical Properties

• Melting Point: 106 °C
• Boiling Point: 106.4°C at 760 mmHg
• Flash Point: 4.4°C
• Appearance: /
• Density: 0.9366 g/cm3
• Vapor Pressure: 28.3mmHg at 25°C
• CAS DataBase Reference: Piperidinium acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidinium acetate(4540-33-4)
• EPA Substance Registry System: Piperidinium acetate(4540-33-4)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 4540-33-4(Hazardous Substances Data)

Usage

Chemical Properties

white solid

InChI:InChI=1/C5H11N.C2H4O2/c1-2-4-6-5-3-1;1-2(3)4/h6H,1-5H2;1H3,(H,3,4)

Upstream product

• 107-91-5 cyanoacetic acid amide 
• 1122-98-1 1-cyclopentyl-propan-2-one 
• 109-94-4 formic acid ethyl ester 
• 5586-88-9 1-(4-chlorophenyl)propan-2-one 
• 41894-93-3 hexahydro-indan-2-one 
• 6975-60-6 1-furan-2-yl-propan-2-one 
• 206666-54-8 [2-(4,5-Dimethyl-2-piperidin-1-yl-[1,3]dithiol-2-yl)-benzo[1,3]dithiol-2-yl]-phosphonic acid diethyl ester 
• 110-89-4 piperidine 
• 64-19-7 acetic acid 

Downstream Products

• 79512-87-1 11t-(4-methoxy-phenyl)-undeca-2t,4t,6t,8t,10-pentaenal 
• 28790-87-6 ethyl 1,2-dimethyl-4-oxocyclohex-2-ene-1-carboxylate 
• 80466-34-8 2,4-hexadienal 
• 17609-31-3 2,4,6-octatrienal 
• 40650-87-1 2,4,6,8-decatetraenal 
• 779-90-8 1,3,5-triacetylbenzene 
• 23071-56-9 1-(4-Dimethylaminophenylimino-)-2-keto-2-(4-tolyl)-propionitril 
• 60998-25-6 pentadeca-2,4-dienal 
• 6460-63-5 7-phenyl-hepta-2,4,6-trienal 
• 747-90-0 3,5-cholestadiene 
• 24512-96-7 ethyl (Z)-2-azido-3-phenylacrylate 
• 599175-23-2 ethyl 4-azido-2-diazo-5-hydroxy-3-oxo-5-phenylpentanoate 
• 865851-49-6 2-(4'-chlorobenzylidene)-4-methoxy-7-piperidinocarbonyloxy-2,3-dihydro-benzo[b]thiophen-3-one 
• 865851-50-9 2-(3'-chlorobenzylidene)-4-methoxy-7-piperidinocarbonyloxy-2,3-dihydro-benzo[b]thiophen-3-one 

Relevant articles and documents

Regioselective one-pot synthesis and anti-proliferative and apoptotic effects of some novel tetrazolo[1,5-a]pyrimidine derivatives

An easy and efficient route for the synthesis of some tetrazolo[1,5-a]-pyrimidine derivatives was described through the reaction of sodium salts of formyl cycloalkanones with 5-aminotetrazole monohydrate. The derivative 6,7,8,9-tetrahydrotetrazolo[1,5-a]quinazoline (6b) has profound anti-tumor cytotoxic effects against Ehrlich ascites carcinoma (EAC) both in vivo and in vitro and against hepatocellular carcinoma (HepG2) cell line in vitro. These anti-tumor effects may be mediated via stimulation of cell cycle arrest and apoptosis through down-regulation of Bcl-2 and up-regulation of p53 transcription factors.

Impact of an aryl bulky group on a one-pot reaction of aldehyde with malononitrile and: N-substituted 2-cyanoacetamide

In this study, we successfully explored the effect of steric hindrance on the one-pot reaction of different aryl aldehydes with malononitrile and N-substituted 2-cyanoacetamide in the presence of piperidinium acetate as the catalyst. It involved the Knoevenagel condensation of the aldehyde and malononitrile to produce arylidene malononitrile as an intermediate, which was further treated with N-substituted 2-cyanoacetamide to give 6-Amino-2-pyridone-3,5-dicarbonitrile derivatives when the less steric bulky group was involved. High steric hindrance changed the earlier reaction route and gave N-substituted 2-cyanoacrylamides via a slower route.

MACROCYCLIC LACTONES AS FRAGRANCES

The present invention refers to methyl-substituted double-unsaturated macrocyclic lactones comprising 14 to 17 ring atoms of formula (I) wherein n and m are independently selected from 1, 2, 3 and 4 with the proviso that 3 ≤ n + m ≤ 6. The invention relates furthermore to their use as odorant and fragrance composition comprising them.