4541-94-0Relevant academic research and scientific papers
1, 3-conjugated diene compound and preparation method and application thereof
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Paragraph 0166-0170; 0352-0356, (2019/06/27)
The invention discloses a 1, 3-conjugated diene compound and a preparation method and application thereof. The invention provides a preparation method of the 1, 3-conjugated diene compound. The preparation method comprises the following steps: in an organic solvent and in the presence of a palladium catalyst, a phosphine ligand and an alkaline reagent, carrying out 1, 4-Pd migration/suzuki coupling reaction on an aromatic halide containing structural fragment shown in formula I and an alkenyl boron compound containing the structural fragment shown in formula II to obtain the compound containing a structural fragment of the 1, 3-conjugated diene shown in formula III. The preparation method has higher stereoselectivity and product configuration uniformity; a substrate has good universality,and is compatible with electron-deficient olefins, electron-rich olefins and polysubstituted olefins; and the method has the characteristics of mild reaction conditions, wide functional group compatibility and the like. The 1, 3-butadiene compound provided by the invention has high aggregation induced luminescence effect.
