454693-98-2Relevant articles and documents
Design and synthesis of novel C2-symmetric chiral piperazines and an application to asymmetric acylation of σ-symmetric 1,2-diols
Nakamura, Daisuke,Kakiuchi, Kiyomi,Koga, Kenji,Shirai, Ryuichi
, p. 6139 - 6142 (2006)
(Chemical Equation Presented) A novel alicyclic chiral C 2-symmetric piperazine, (S,S)-7, is designed and synthesized from L-proline. Benzoylation of a series of cyclic and acyclic meso-1,2-diols with a catalytic amount of (S,S)-7 and CuCl2 provided optically active monobenzoates with high enantioselectivity.