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1-(4-chloroquinolin-2-yl)ethan-1-one is a chemical compound with the molecular formula C11H8ClNO. It is a derivative of quinoline, a heterocyclic aromatic compound, and features a chloro substituent at the 4-position and an ethanone group at the 1-position. 1-(4-chloroquinolin-2-yl)ethan-1-one is known for its potential applications in the synthesis of various pharmaceuticals and agrochemicals, particularly as an intermediate in the production of certain quinoline-based drugs. Its chemical structure and properties make it a valuable building block in organic chemistry, with potential uses in the development of new compounds with specific therapeutic or pesticidal effects.

4552-42-5

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4552-42-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4552-42-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,5,5 and 2 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 4552-42:
(6*4)+(5*5)+(4*5)+(3*2)+(2*4)+(1*2)=85
85 % 10 = 5
So 4552-42-5 is a valid CAS Registry Number.

4552-42-5Downstream Products

4552-42-5Relevant academic research and scientific papers

Syntheses of acetylquinolines and acetylisoquinolines via palladium-catalyzed coupling reactions

Legros, Jean-Yves,Primault, Ga?lle,Fiaud, Jean-Claude

, p. 2507 - 2514 (2001)

Acetylquinolines and acetylisoquinolines were obtained from the corresponding chloro-, bromo- or trifluoromethylsulfonyloxy-heteroaromatics via four different palladium-catalyzed coupling reactions: (i) Stille coupling with tri(n-butyl)-1-ethoxyvinylstannane; (ii) Negishi coupling with 1-ethoxyvinylzinc chloride; (iii) cross-coupling with tri(1-ethoxyvinyl)indium; (iv) Heck arylation of n-butyl vinyl ether.

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