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2-PHENYL-PYRROLIDINE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER is a pyrrolidine carboxylic acid derivative with versatile reactivity, commonly utilized in the synthesis of pharmaceuticals and organic compounds. Its tert-butyl ester form enhances stability and solubility, making it a valuable component in chemical and pharmaceutical processes. It is also being explored for potential medicinal applications, including anti-inflammatory, antifungal, and antiviral properties, as well as in the treatment of neurodegenerative diseases like Alzheimer's and Parkinson's.

455955-08-5

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455955-08-5 Usage

Uses

Used in Pharmaceutical Synthesis:
2-PHENYL-PYRROLIDINE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER is used as a key intermediate in the synthesis of various pharmaceuticals and organic compounds due to its versatile reactivity and increased stability provided by the tert-butyl ester group.
Used in Medicinal Applications:
In the field of medicine, 2-PHENYL-PYRROLIDINE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER is used as an anti-inflammatory, antifungal, and antiviral agent, leveraging its potential therapeutic properties to combat various conditions.
Used in Neurodegenerative Disease Treatment:
2-PHENYL-PYRROLIDINE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER is being studied for its potential use in treating neurodegenerative diseases such as Alzheimer's and Parkinson's, where its chemical properties may contribute to disease management and symptom alleviation.
Used in Chemical Processes:
In the chemical industry, 2-PHENYL-PYRROLIDINE-1,3-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER is used to improve the stability and solubility of compounds in various chemical processes, enhancing the efficiency and effectiveness of these processes.

Check Digit Verification of cas no

The CAS Registry Mumber 455955-08-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,5,5,9,5 and 5 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 455955-08:
(8*4)+(7*5)+(6*5)+(5*9)+(4*5)+(3*5)+(2*0)+(1*8)=185
185 % 10 = 5
So 455955-08-5 is a valid CAS Registry Number.

455955-08-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[(2-methylpropan-2-yl)oxycarbonyl]-2-phenylpyrrolidine-3-carboxylic acid

1.2 Other means of identification

Product number -
Other names 2-Phenyl-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:455955-08-5 SDS

455955-08-5Downstream Products

455955-08-5Relevant articles and documents

SUBSTITUTED PYRROLIDINE AMIDES V

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, (2021/01/22)

The invention relates to compounds according to general formula (I), which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.

Diastereoselective access to enantiomerically pure cis-2,3-disubstituted pyrrolidines

Delaye, Pierre-Olivier,Pradhan, Tanin K.,Lambert, Emilie,Vasse, Jean-Luc,Szymoniak, Jan

experimental part, p. 3395 - 3406 (2010/08/20)

A straightforward access to enantiomerically pure 2,3-disubstituted pyrrolidines is reported that involves diastereoselective allylation of (R)-phenylglycinol-derived imines and a sequential hydrozirconation-cyclization. A number of pyrrolidine derivatives bearing aryl, heteroaryl, alkyl and alkenyl groups have been prepared in this way. Such compounds are useful building blocks in the synthesis of molecules of biological interest, as illustrated by the syntheses of proline derivatives and the naturally occurring alkaloid (-)-isoretronecanol.

3-AMINO-2-PHENYLPYRROLIDINE DERIVATIVES

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Page/Page column 78, (2010/02/14)

3-amino-2-phenylpyrrolidine compounds useful as NK-1 antagonists, with pharmaceutical compositions and methods of treatment comprising same, are disclosed.

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