4569-35-1

Upstream product

• 4920-02-9 diphenyl((trimethylsilyl)methyl)phosphine oxide 
• 75-07-0 acetaldehyde 
• 829-85-6 diphenylphosphane 
• 590-13-6 (Z)-1-propenyl bromide 
• 4559-70-0 Diphenylphosphine oxide 
• 683-08-9 Diethyl methylphosphonate 
• 1499-21-4 Diphenylphosphinic chloride 
• 756-79-6 dimethyl methane phosphonate 

Downstream Products

• 131480-33-6 3-diphenylphosphinyl-2,6,6-trimethylhexahydropyrrolo<1,2-b>isoxazole 
• 4608-06-4 (E)-diphenyl-(prop-1-en-1-yl)phosphine oxide 
• 103785-70-2 (R*,R*)-3-Diphenylphosphinoylbutan-2-ol 
• 148003-96-7 diphenyl(2-trimethylsilylpropyl)phosphine oxide 
• 148003-78-5 2-propyl(diphenyl)phosphine oxide 
• 1261157-93-0 [2-(tert-butyldiphenylsilyl)propyl]diphenylphosphane oxide 
• 4141-48-4 allyldiphenylphosphine oxide 
• 1261158-14-8 [2-(phenylthio)propyl]diphenylphosphane oxide 
• 1261158-17-1 C₁₉H₂₃O₂P 

Relevant academic research and scientific papers

Regio- and stereospecific cleavage of silyl- and disilylepoxides with lithium diphenylphosphide

Unsubstituted or α- and β-C-substituted silylepoxides react stereospecifically with lithium diphenylphosphide, optionally followed by methylation, to give vinylphosphonium iodides or vinylphosphine oxides resulting from α-opening and silyl enol ethers, vi

A Regiocontrolled and Stereocontrolled Synthesis of Allylsilanes from β-Silyl Enolates

The α-lithiated diphenylphosphine oxides 3 react with methyl iodide to give the phosphine oxides 4 and 5 in a ratio 3-4:1.The corresponding reaction with aldehydes gives all four diastereomeric alcohols 7-10, which are not suitable for the synthesis of allylsilanes by a Wittig-Horner reaction.The β-dimethyl(phenyl)silyl enolates 13-15 and 25-28 react with aldehydes to give aldol products with high diastereoselectivity.The benzyl and allyl ester groups can be cleaved from these aldols to give the acids 16-18 and 29-32.The acids, in turn, can be induced to undergo dec arboxylative elimination stereospecifically either in a syn or an anti sense to give the allylsilanes 19, 20, 23, 24, 33, 34 and 39-41.A similar series of reactions can be carried out with the β-trimethylsilyl enolates 45 and 46 giving the allylsilanes 49, 50, 53 and 54.

PREPARATION OF DIPHENYLVINYLPHOSPHINE OXIDES BY THE PCP PROCESS. CHOICE OF THE LEAVING CROUP.

Carbanionic conversion of alkyl into vinylphosphonates is extended to the preparation of diphenylvinylphosphine oxides.Obtention of pure products in optimized yields is closely related to the choice of the phosphate leaving group.

Palladium-Catalysed Synthesis of Alkenyldiphenyl- and Alkenylbenzylphenylphosphine Oxides

Alkenyldiphenyl- and Alkenylbenzylphenylphosphine oxides 3 were prepared by the palladium catalysed reaction of alkenyl bromides 1 with phosphine oxides 2a or 2b.