45695-03-2 Usage
Uses
Used in Pharmaceutical Synthesis:
(S)-1-PYRIDIN-2-YL-ETHYLAMINE is used as a building block for the synthesis of pharmaceuticals, contributing to the development of new drugs with improved efficacy and selectivity. Its chiral nature allows for the creation of enantiomerically pure compounds, which is crucial for ensuring the desired biological activity and minimizing potential side effects.
Used in Agrochemical Synthesis:
In the agrochemical industry, (S)-1-PYRIDIN-2-YL-ETHYLAMINE serves as a key intermediate in the synthesis of various agrochemicals, including pesticides and herbicides. Its incorporation into these products can enhance their effectiveness and selectivity, leading to improved crop protection and reduced environmental impact.
Used as a Chiral Auxiliary in Asymmetric Synthesis:
(S)-1-PYRIDIN-2-YL-ETHYLAMINE is utilized as a chiral auxiliary in asymmetric synthesis, a technique that allows for the selective formation of one enantiomer over another. This is particularly important in the production of enantiomerically pure compounds, which can exhibit different biological activities and pharmacological properties. The use of (S)-1-PYRIDIN-2-YL-ETHYLAMINE as a chiral auxiliary can improve the yield and selectivity of asymmetric reactions, facilitating the synthesis of complex molecules with specific chiral centers.
Used in Organic Chemistry Research:
As an important intermediate in organic chemistry, (S)-1-PYRIDIN-2-YL-ETHYLAMINE is employed in various research applications, including the study of reaction mechanisms, the development of new synthetic methods, and the exploration of novel chemical transformations. Its unique structural features and reactivity make it a valuable tool for advancing the field of organic chemistry and discovering new applications for this versatile compound.
Check Digit Verification of cas no
The CAS Registry Mumber 45695-03-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,5,6,9 and 5 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 45695-03:
(7*4)+(6*5)+(5*6)+(4*9)+(3*5)+(2*0)+(1*3)=142
142 % 10 = 2
So 45695-03-2 is a valid CAS Registry Number.
45695-03-2Relevant academic research and scientific papers
Biocatalytic transamination with near-stoichiometric inexpensive amine donors mediated by bifunctional mono- and di-amine transaminases
Galman, James L.,Slabu, Iustina,Weise, Nicholas J.,Iglesias, Cesar,Parmeggiani, Fabio,Lloyd, Richard C.,Turner, Nicholas J.
supporting information, p. 361 - 366 (2017/08/14)
The discovery and characterisation of enzymes with both monoamine and diamine transaminase activity is reported, allowing conversion of a wide range of target ketone substrates with just a small excess of amine donor. The diamine co-substrates (putrescine, cadaverine or spermidine) are bio-derived and the enzyme system results in very little waste, making it a greener strategy for the production of valuable amine fine chemicals and pharmaceuticals.
But-2-ene-1,4-diamine and But-2-ene-1,4-diol as Donors for Thermodynamically Favored Transaminase- and Alcohol Dehydrogenase-Catalyzed Processes
Martínez-Montero, Lía,Gotor, Vicente,Gotor-Fernández, Vicente,Lavandera, Iván
supporting information, p. 1618 - 1624 (2016/10/13)
Both cis- and trans-but-2-ene-1,4-diamines have been prepared and efficiently applied as sacrificial cosubstrates in enzymatic transamination reactions. The best results were obtained with the cis-diamine. The thermodynamic equilibrium of the stereoselective transamination process is shifted to the amine formation due to tautomerization of 5H-pyrrole into 1H-pyrrole, achieving high conversions (78–99%) and enantiomeric excess (up to >99%) by using a small excess of the amine donor. Furthermore, when the reaction proceeded, a strong coloration was observed due to polymerization of 1H-pyrrole. A structurally related compound, cis-but-2-ene-1,4-diol, has been utilized as cosubstrate in different alcohol dehydrogenase (ADH)-mediated bioreductions. In this case, high conversions (91–99%) were observed due to a lactonization process. Both strategies are convenient from both synthetic and atom economy points of view in the production of valuable optically active products. (Figure presented.).
