457058-35-4Relevant academic research and scientific papers
Formation of 1,3-thiazol-5(4H)-imines and 1,3-oxazol-5(4H)-imines in Aib-containing thiopeptides
Breitenmoser, Roland A.,Linden, Anthony,Heimgartner, Heinz
, p. 990 - 1018 (2007/10/03)
When tripeptides of type Axxt-Aib-Axx-OH were coupled with amino acid methyl esters by means of commonly used coupling reagents, the formation of 1,3-thiazol-5(4H)-imines and 1,3-oxazol-5(4H)-imines was observed. With the aim of understanding w
