45775-91-5

Usage

Type of compound

Cyclic organic compound

Usage

Synthesis of various organic compounds and pharmaceuticals

Primary study

Potential use as a building block in organic chemistry and drug development

Application fields

Materials science and chemical research

Safety precautions

Due to chemical reactivity and potential health hazards, proper safety measures should be taken when handling 1,2-Cyclobutanedicarbonyl dichloride, (1R-trans)- (9CI).

Upstream product

• 1124-13-6 (+/-)-(1S,2S)-cyclobutane-1,2-dicarboxylic acid 
• 124-04-9 Adipic acid 
• 868-72-4 dimethyl 2,5-dibromohexanedioate 
• 29548-86-5 2,5-dibromohexanedioyl dichloride 
• 3396-14-3 (RR,SS)-trans-1,2-cyclobutanedicarboxylic acid 
• 14132-45-7 dimethyl 1-cyanocyclobutane-1,2-dicarboxylate 
• 2144-31-2 cyclobutane-1,1,2-tricarboxylic acid 
• 111-50-2 Adipic acid dichloride 

Downstream Products

• 70774-29-7 trans-1,2-bis(hydroxymethyl)cyclopentane 
• 59236-82-7 (1S,2S)-Cyclobutane-1,2-dicarboxylic acid mono-(1-biphenyl-4-yl-pentyl) ester 

Relevant academic research and scientific papers

HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF

Provided herein are heteroaryl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. In one embodiment, the compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as CNS disorders and metabolic disorders, including, but not limited to, e.g., neurological disorders, psychosis, schizophrenia, obesity, and diabetes.

The synthesis and use in asymmetric epoxidation of metal salen complexes derived from enantiopure trans-cyclopentane- and cyclobutane-1,2-diamine

A complete synthesis of enantiopure trans-cyclopentane-1,2-diamine and trans-cyclobutane-1,2-diamine is described. These diamines have been used as components of novel chiral salen ligands whose chromium and manganese complexes were then evaluated as oxygen transfer agents in the asymmetric epoxidation of alkenes.