Welcome to LookChem.com Sign In|Join Free
  • or
(4'-TRIFLUOROMETHYLBIPHENYL-4-YL)-METHANOL, also known as (4'-trifluoromethylbiphenyl-4-yl)-methanol, is a colorless liquid chemical compound characterized by a biphenyl ring with a trifluoromethyl group at the 4' position and a methanol group at the 4 position. It has a molecular formula of C14H11F3O and is known for its potential applications in various industries due to its unique structural features.

457889-46-2

Post Buying Request

457889-46-2 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

457889-46-2 Usage

Uses

Used in Organic Synthesis:
(4'-TRIFLUOROMETHYLBIPHENYL-4-YL)-METHANOL is used as a building block in organic synthesis for the preparation of other chemical compounds. Its unique structure allows it to be a valuable intermediate in the synthesis of various organic molecules.
Used in Pharmaceutical Industry:
(4'-TRIFLUOROMETHYLBIPHENYL-4-YL)-METHANOL may have potential applications in the pharmaceutical industry due to its structural features. Its trifluoromethyl and methanol groups could contribute to the development of new drugs with specific therapeutic properties. However, further research and testing are needed to fully understand its potential in this field.
Used in Agrochemical Industry:
Similarly, (4'-TRIFLUOROMETHYLBIPHENYL-4-YL)-METHANOL may also find use in the agrochemical industry, where its structural features could be leveraged to develop new agrochemicals with targeted effects on pests or diseases. Further investigation is required to explore its potential applications and benefits in this area.

Check Digit Verification of cas no

The CAS Registry Mumber 457889-46-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,5,7,8,8 and 9 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 457889-46:
(8*4)+(7*5)+(6*7)+(5*8)+(4*8)+(3*9)+(2*4)+(1*6)=222
222 % 10 = 2
So 457889-46-2 is a valid CAS Registry Number.

457889-46-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name [4-[4-(trifluoromethyl)phenyl]phenyl]methanol

1.2 Other means of identification

Product number -
Other names 4-(4-trifluoromethylphenyl)-benzyl alcohol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:457889-46-2 SDS

457889-46-2Downstream Products

457889-46-2Relevant academic research and scientific papers

CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE

-

Paragraph 00470-00472, (2019/06/11)

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with the enzyme ceramide galactosyltransferase (CGT), such as, for example, lysosomal storage diseases. Examples of lysosomal storage diseases include, for example, Krabbe disease and Metachromatic Leukodystrophy.

RADIOLABELED DARAPLADIB AND ANALOGS THEREOF AND THEIR USE AS IMAGING COMPOUNDS

-

Page/Page column 44, (2019/04/26)

The present inventors have developed new radiolabeled Darapladib and analogs thereof which can be used for the specific detection of vulnerable atherosclerotic plaques by targeting lipoprotein-associated phospholipase A2 (Lp-PLA2) which is a biomarker of

Disubstituted beta-lactones as inhibitors of N-acylethanolamine acid amidase (NAAA)

-

Page/Page column 122, (2016/06/28)

The present invention provides compounds and pharmaceutical compositions for inhibiting N-acylethanolamine acid amidase (NAAA). Inhibition of NAAA is contemplated as a method to sustain the levels of palmitoylethanolamide (PEA) and oleylethanolamide (OEA), two substrates of NAAA, in conditions characterized by reduced concentrations of PEA and OEA. The invention also provides methods for treating inflammatory diseases and pain, and other disorders in which decreased levels of PEA and OEA are associated with the disorder.

AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE

-

, (2014/05/20)

The present invention relates to the filed of pharmarcutical chemistry, and in particular, to a novel class of azole compounds represented by general formula (I), (II) or (III) amd a preparation method thereof, a pharmarcutical composition with the compounds as active components, and a use of the azole compounds and the pharmarcutical composition in the preparation of a medicament for treatment of diseases associated with Lp-PLA2 enzyme activities, wherein each substituent is as deinfed in the specifictaion.

AZOLE HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE

-

, (2014/06/25)

The present invention relates to the field of pharmaceutical chemistry, and in particular, to a novel class of azole compounds represented by general formula (I), (II) or (III) and a preparation method thereof, a pharmaceutical composition with the compounds as active components, and a use of the azole compounds and the pharmaceutical composition in the preparation of a medicament for treatment of diseases associated with Lp-PLA2 enzyme activities, wherein each substituent is as defined in the specification.

Synthesis, biological evaluation, and 3D QSAR study of 2-methyl-4-oxo-3-oxetanylcarbamic acid esters as N -acylethanolamine acid amidase (NAAA) inhibitors

Ponzano, Stefano,Berteotti, Anna,Petracca, Rita,Vitale, Romina,Mengatto, Luisa,Bandiera, Tiziano,Cavalli, Andrea,Piomelli, Daniele,Bertozzi, Fabio,Bottegoni, Giovanni

supporting information, p. 10101 - 10111 (2015/02/02)

N-(2-Oxo-3-oxetanyl)carbamic acid esters have recently been reported to be noncompetitive inhibitors of the N-acylethanolamine acid amidase (NAAA) potentially useful for the treatment of pain and inflammation. In the present study, we further explored the

DISUBSTITUTED BETA-LACTONES AS INHIBITORS OF N-ACYLETHANOLAMINE ACID AMIDASE (NAAA)

-

Paragraph 0353, (2013/06/06)

The present invention provides compounds and pharmaceutical compositions for inhibiting N-acylethanolamine acid amidase (NAAA). Inhibition of NAAA is contemplated as a method to sustain the levels of palmitoylethanolamide (PEA) and oleylethanolamide (OEA), two substrates of NAAA, in conditions characterized by reduced concentrations of PEA and OEA. The invention also provides methods for treating inflammatory diseases and pain, and other disorders in which decreased levels of PEA and OEA are associated with the disorder.

Dicarboxylic Acid Derivatives and their Use

-

Page/Page column 18-19, (2010/03/02)

The present application relates to novel dicarboxylic acid derivatives, process for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, es

PYRIMIDINE DERIVATIVES AS ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE

-

Page/Page column 39, (2010/04/03)

Disclosed are compounds of formula (I) and or salts thereof which activate soluble guanylate cyclase (sGC), pharmaceutical compositions containing them, their use in the manufacture of a medicament for teating cardiovascular diseases, and processes for their preparation.

Heterocyclic compounds with carboxyl isostere groups and their use for the treatment of cardiovascular diseases

-

Page/Page column 38, (2009/09/25)

The present application relates to novel heterocyclic compounds, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, especia

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 457889-46-2