457930-94-8

Upstream product

• 142-68-7 TETRAHYDROPYRANE 
• 106-42-3 para-xylene 
• 142-71-2 copper diacetate 
• 104-84-7 para-methylbenzylamine 
• 766-97-2 4-n-methylphenylacetylene 
• 589-18-4 4-Methylbenzyl alcohol 
• 104-87-0 4-methyl-benzaldehyde 

Relevant academic research and scientific papers

Anchoring of a Copper(II)-Schiff Base Complex onto Silica-Coated Ferrite Nanoparticles: A Magnetically Separable Catalyst for Oxidative C-O Coupling by Direct C(sp2)-H and C(sp3)-H Bond Activation

A novel catalyst consisting of a Schiff base-copper complex on surface-modified silica-coated ferrite nanoparticles was been prepared and used for oxidative C-O cross-coupling reactions of 1,3-dicarbonyl compounds with formamides for the synthesis of enol

Generation of bis-Acyl ketals from esters and benzyl amines under oxidative conditions

Treatment of benzylamines with esters at an elevated temperature are expected to give amides. However, in the presence of TBAI/TBHP, esters possessing a methylene carbon α-to oxygen with benzylamines provide bis-esters rather than the expected amides. Benzylamines under oxidative conditions generate less nucleophilic carboxylates, which couples at the sp3 C-H bonds of esters and cyclic ethers to give bis-acyl ketals and α-acyloxy ethers, respectively.

Cyclic ethers to esters and monoesters to bis-esters with unconventional coupling partners under metal free conditions via sp3 C-H functionalisation

An efficient metal free oxidative esterification of sp3 C-H bonds (adjacent to an oxygen atom) in simple solvents like 1,4-dioxane, tetrahydropyran, tetrahydrofuran and ethyl acetate has been achieved using terminal aryl alkenes and alkynes as

Copper-Catalyzed Formation of C-O Bonds by Oxidative Coupling of Benzylic Alcohols with Ethers

The copper-catalyzed formation of C-O bonds by oxidative coupling of benzylic alcohols with ethers was realized in open air. A series of α-acyloxy ethers were obtained in good yields with aqueous tert-butyl hydroperoxide as the oxidant. The copper-catalyzed formation of C-O bonds by oxidative coupling of benzylic alcohols with ethers is realized in open air. A series of α-acyloxy ethers were obtained in good yields with aqueous tert-butyl hydroperoxide as the oxidant.

Copper-catalyzed acyloxylation of the C(sp3)-H bond adjacent to an oxygen by a cross-dehydrogenative coupling approach

The acyloxylation of the C(sp3)-H bond adjacent to oxygen by adopting a copper catalyzed dehydrogenative cross-coupling reaction between simple ethers and benzyl alcohols has been disclosed. The advantages of the dehydrogenative cross-coupling reaction are the adoption of unactivated ethers as substrates and good tolerance of many functional groups. This journal is

Copper catalyzed C-O bond formation via oxidative cross-coupling reaction of aldehydes and ethers

A practical and efficient construction of C-O bonds via oxidative cross-coupling reaction of aldehydes and ethers has been realized under open air. When 2 mol% copper was used as the catalyst, various α-acyloxy ethers were obtained with up to 93% isolated

Copper-catalyzed esterification of alkylbenzenes with cyclic ethers and cycloalkanes via C(sp3)-H activation following cross-dehydrogenative coupling

A copper-catalyzed cross-dehydrogenative coupling strategy has been developed for the synthesis of two classes of esters from simple solvents. The reaction of methylarenes with cyclic ethers resulted in α-acyloxy ethers involving four sp3 C-H cleavages, while treatment of methylarenes with cycloalkanes led to the formation of allyl esters at the expense of six consecutive sp3 C-H bonds.