458567-80-1Relevant articles and documents
A novel strategy for the synthesis of medium-sized lactams
Bieraeugel, Hans,Jansen, T. Paul,Schoemaker, Hans E.,Hiemstra, Henk,Van Maarseveen, Jan H.
, p. 2673 - 2674 (2007/10/03)
(Matrix presented) A novel method for the synthesis of medium-sized lactams based on an auxiliary-mediated combined tethered/templated strategy is presented. Cyclization by a tethered ring-closing metathesis reaction was followed by a templated transannular aminolysis reaction to give seven-to ten-membered lactams in good yields.