177780-96-0

Basic information

• Product Name: 2-[(prop-2-en-1-ylamino)methyl]phenol
• Synonyms: 2-[(prop-2-en-1-ylamino)methyl]phenol;Phenol, 2-[(2-propen-1-ylamino)methyl]-
• CAS NO: 177780-96-0
• Molecular Formula: C₁₀H₁₃NO
• Molecular Weight: 163.22
• Mol File: 177780-96-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 271.0±20.0 °C(Predicted)
• Appearance: /
• Density: 1.035±0.06 g/cm3(Predicted)
• PKA: 10.36±0.30(Predicted)
• CAS DataBase Reference: 2-[(prop-2-en-1-ylamino)methyl]phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(prop-2-en-1-ylamino)methyl]phenol(177780-96-0)
• EPA Substance Registry System: 2-[(prop-2-en-1-ylamino)methyl]phenol(177780-96-0)

Safety Data

• Hazardous Substances Data: 177780-96-0(Hazardous Substances Data)

Usage

General Description

2-[N-(prop-2'-enyl)aminomethyl]phenol is a chemical compound with the molecular formula C10H13NO. It is a derivative of phenol with a prop-2'-enylamine substituent attached to the nitrogen atom. 2-[N-(prop-2'-enyl)aminomethyl]phenol is commonly used in the production of pharmaceuticals and as a reagent in organic synthesis. It exhibits a wide range of biological activities, including antifungal and anti-inflammatory properties, making it a valuable compound in medical research. Additionally, it has potential applications as an antioxidant and as a precursor in the development of new drug candidates. Overall, 2-[N-(prop-2'-enyl)aminomethyl]phenol is a versatile and important chemical with diverse uses in the pharmaceutical and chemical industries.

Upstream product

• 90-02-8 salicylaldehyde 
• 107-11-9 1-amino-2-propene 
• 27895-70-1 2-((allylimino)methyl)phenol 

Downstream Products

• 406725-61-9 2-[(allyl-pent-4-enyl-amino)-methyl]-phenol 
• 458567-86-7 oct-7-enoic acid 2-[(allyl-tert-butoxycarbonyl-amino)-methyl]-phenyl ester 
• 458567-83-4 hept-6-enoic acid 2-[(allyl-tert-butoxycarbonyl-amino)-methyl]-phenyl ester 
• 458567-80-1 hex-5-enoic acid 2-[(allyl-tert-butoxycarbonyl-amino)-methyl]-phenyl ester 
• 458567-77-6 pent-4-enoic acid 2-[(allyl-tert-butoxycarbonyl-amino)-methyl]-phenyl ester 
• 458567-74-3 but-3-enoic acid 2-[(allyl-tert-butoxycarbonyl-amino)-methyl]-phenyl ester 
• 458568-14-4 allyl-(2-hydroxy-benzyl)-carbamic acid tert-butyl ester 
• 60405-97-2 2-((diallylamino)methyl)phenol 
• 259671-80-2 2-[(allyl-but-3-enyl-amino)-methyl]-phenol 

Relevant articles and documents

Observations concerning the synthesis of heteroatom-containing 9-membered benzo-fused rings by ring-closing metathesis

A set of benzo-fused dienes with a 1,9-relationship and containing a variety of nitrogen and oxygen heteroatoms was readily synthesized. These dienes were then treated with the Grubbs second generation catalyst with the aim of synthesizing the 9-membered benzannelated heterocycles containing two heteroatoms (either O,O, NR,NR or O,NR where R = Ts or Boc). As previously observed in the literature, many of the dienes did not give the expected ring-closed product. However, a number of the desired products did form, namely with the 1,2-dihydrobenzo[c][1,5]oxazonin-7(5H)-one, 5,7-dihydrobenzo[b][1,5]oxazonine-6(2H)-carboxylate and 2,5,6,7-tetrahydrobenzo[b][1,5]oxazonine cores, albeit in poor yields. Rather surprisingly, the N-allyl-N-(2-(N-allyl-4-methylphenylsulfonamido)benzyl)-4-methylbenzenesulfonamide scaffold gave the desired ring-closed 1,6-ditosyl-2,5,6,7-tetrahydro-1H-benzo[b][1,5]diazonine in a high yield. Furthermore, when treated with the catalyst [RuClH(CO)(PPh3)3] the alkene isomerized into conjugation only with the benzylic NTs group and not with the phenyl NTs group to afford the 1,6-ditosyl-2,3,6,7-tetrahydro-1H-benzo[b][1,5]diazonine structure.

Synthesis of novel α-substituted and α,α-disubstituted amino acids by rearrangement of ammonium ylides generated from metal carbenoids

(equation presented) A new and general four-step synthesis of protected a-substituted and α,α-disubstituted amino acids has been developed. The key step involves intramolecular ammonium ylide generation from a copper carbenoid with concomitant [2,3] rearr

Synthesis and Insecticidal Activity of 2-Alkoxy-4H-1,3,2-benzoxazaphosphorin-2-thiones

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