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CAS

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45893-20-7

8-Aminohypoxanthine is a purine nucleoside analog that has been studied for its potential applications in various fields, particularly as an inhibitor of purine nucleoside phosphorylase in human erythrocytes. 8-AMinohypoxanthine is structurally similar to the naturally occurring purine nucleosides, which allows it to interact with specific enzymes and proteins.

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  • 45893-20-7 Structure

  • Basic information

    1. Product Name: 8-AMinohypoxanthine
    2. Synonyms: 8-AMinohypoxanthine
    3. CAS NO:45893-20-7
    4. Molecular Formula: C5H4N5O
    5. Molecular Weight: 150.11816
    6. EINECS: N/A
    7. Product Categories: Nucleotides, Bases & Related Reagents
    8. Mol File: 45893-20-7.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 2.19±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
    8. Solubility: Aqueous Base (Slightly)
    9. PKA: 8.58±0.70(Predicted)
    10. CAS DataBase Reference: 8-AMinohypoxanthine(CAS DataBase Reference)
    11. NIST Chemistry Reference: 8-AMinohypoxanthine(45893-20-7)
    12. EPA Substance Registry System: 8-AMinohypoxanthine(45893-20-7)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 45893-20-7(Hazardous Substances Data)

45893-20-7 Usage

Uses

Used in Pharmaceutical Applications:
8-Aminohypoxanthine is used as a purine nucleoside phosphorylase inhibitor for its potential role in the treatment of certain diseases. Purine nucleoside phosphorylase (PNP) is an enzyme involved in the purine salvage pathway, which is crucial for the synthesis of nucleotides and the regulation of immune responses. Inhibition of PNP can lead to the accumulation of toxic metabolites, which may be useful in targeting cancer cells or modulating immune responses in autoimmune diseases.
Used in Research and Development:
8-Aminohypoxanthine is also used as a research tool to study the mechanisms of purine metabolism and the role of PNP in various biological processes. By understanding the interactions between 8-Aminohypoxanthine and PNP, researchers can gain insights into the development of new therapeutic strategies for diseases related to purine metabolism dysregulation.
Used in Drug Design and Synthesis:
8-Aminohypoxanthine serves as a starting point for the design and synthesis of new drugs targeting purine nucleoside phosphorylase or other related enzymes. Its structural similarity to natural purine nucleosides allows for the development of more potent and selective inhibitors, which can be tailored to specific therapeutic needs.

Check Digit Verification of cas no

The CAS Registry Mumber 45893-20-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,5,8,9 and 3 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 45893-20:
(7*4)+(6*5)+(5*8)+(4*9)+(3*3)+(2*2)+(1*0)=147
147 % 10 = 7
So 45893-20-7 is a valid CAS Registry Number.

45893-20-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 8-amino-1,7-dihydro-purin-6-one

1.2 Other means of identification

Product number -
Other names 8-Amino-1,7-dihydro-purin-6-on

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:45893-20-7 SDS

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