8-AMinohypoxanthine

Base Information

• Chemical Name: 8-AMinohypoxanthine
• CAS No.: 45893-20-7
• Molecular Formula: C5H5N5O
• Molecular Weight: 151.12600
• Mol file: 45893-20-7.mol

Synonyms:8-Aminohypoxanthine;8-Amino-1,7-dihydro-purin-6-on;

Chemical Property of 8-AMinohypoxanthine

Chemical Property:

• Melting Point: >300°C
• PKA: 8.58±0.70(Predicted)
• PSA: 100.45000
• Density: 2.19±0.1 g/cm3(Predicted)
• LogP: -0.19040
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility.: Aqueous Base (Slightly)

Purity/Quality:

8-Aminohypoxanthine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 8-Aminohypoxanthine was investigated as a purine nucleoside phosphorylase inhibitor in human erythrocytes.

Technology Process of 8-AMinohypoxanthine

There total 1 articles about 8-AMinohypoxanthine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5,6-diamino-4(3H)-pyrimidinone (1672-50-0) + guanidine nitrate (113-00-8) → 8-amino-1,7-dihydro-purin-6-one (45893-20-7)

Guidance literature:

at 230 ℃;

DOI:10.1021/ja01557a051

Reference yield:

8-amino-1,7-dihydro-purin-6-one (45893-20-7) → 8-amino-1,7-dihydro-purine-6-thione (6223-63-8)

Guidance literature:

With pyridine; tetraphosphorus decasulfide;

DOI:10.1021/ja01557a051

upstream raw materials:

5,6-diamino-4(3H)-pyrimidinone

guanidine nitrate

Downstream raw materials:

8-amino-1,7-dihydro-purine-6-thione