4590-87-8Relevant academic research and scientific papers
Green synthetic investigation and spectral characterization of some spiro pyrazolidine-based heterocycles with potential biological activity
El-Ossaily, Yasser A.,Metwally, Saoud A.,Al-Muailkel, Nayef S.,Fawzy, Ahmed,Ali, Hazim M.,Naffea, Yousra A.
, p. 1729 - 1736 (2020/01/25)
A green, rapid, and efficient methodology is developed for the synthesis of 1-phenyl-3,5-pyrazolidinedione (3) by the reaction of malonic acid with phenyl hydrazine in the presence of phosphorous oxychloride under solvent-free conditions. The later compou
Regioselective synthesis and anti-inflammatory activity of novel dispiro[pyrazolidine-4,3′-pyrrolidine-2′,3″-indoline] -2″,3,5-triones
Hussein, Essam M.,Abdel-Monem, Maisa I.
, p. 71 - 84 (2011/10/05)
Novel dispiro[pyrazolidine-4,3′-pyrrolidine-2′,3″- indoline]-2″,3,5-triones 5a-j were obtained regioselectively by 1,3-dipolar cycloaddition reaction of 4-arylidene-1-phenylpyrazolidine-3,5- diones 2a-e as dipolarophiles with non-stabilized azomethine yli
