459174-50-6

Upstream product

• 64-19-7 acetic acid 
• 444814-26-0 N-[(R)-α-methylbenzyl]aziridine-2(S)-diphenylmethanol 
• 397849-98-8 N-[(R)-(+)-α-methylbenzyl]-2(S)-carboxylic acid (-)-menthol ester 

Downstream Products

• 155836-48-9 tert-butyl [(2R)-3-hydroxy-1,1-diphenylpropan-2-yl]carbamate 
• 143060-31-5 N-(tert-butoxycarbonyl)-3,3-diphenyl-D-alanine 
• 459174-51-7 2(S)-{N-[(R)-α-methylbenzyl]amino}-1,1-diphenyl-1,3-propanediol 

Relevant academic research and scientific papers

An efficient synthesis of N-Boc-D-diphenylalanine from a chiral azirdine-2-carboxylate

N-Boc-D-diphenylalanine was prepared from a commercially available aziridine-2(S)-carboxylate through alkylation, regiospecific aziridine ring opening, and benzylic deoxygenation followed by oxidation in 57% overall yield.