459830-99-0Relevant academic research and scientific papers
1,3-Dihydrobenzo[c]furan nucleoside analogues: Additional studies of the thymine derivative
Egron, David,Perigaud, Christian,Gosselin, Gilles,Aubertin, Anne-Marie,Faraj, Abdesslem,Selouane, Majid,Postel, Denis,Len, Christophe
, p. 4473 - 4475 (2003)
The detailed study of the 1,3-dihydrobenzo[c]furan derivative of thymine is reported. The lack of anti-HIV activity of this compound in cell culture experiments is shown to be related to the inability of the corresponding 5′-triphosphate derivative to int
Enantiomeric d4T analogues and their structural determination
Selouane, Abdelmajid,Vaccher, Claude,Villa, Pierre,Postel, Denis,Len, Christophe
, p. 407 - 413 (2007/10/03)
Asymmetric synthesis of d4T analogues having a benzo[c]furan moiety with two asymmetric carbon atoms was realized using Sharpless asymmetric dihydroxylation as the key step in a synthesis starting from o-phthalaldehyde. Enantiomeric purities were determin
