4599-10-4

Upstream product

• 19933-22-3 1-phenyl-pyrazolidine-3,5-dione 
• 555-16-8 4-nitrobenzaldehdye 
• 100-63-0 phenylhydrazine 

Downstream Products

• 106584-29-6 1-phenyl-2-methyl-4-(4-nitrobenzyliden)-3,5-dioxopyrazolidine 
• 106584-34-3 1-phenyl-2,4-dimethyl-4-(α-methoxy-p-nitrobenzyl)-3,5-dioxopyrazolidine 
• 106584-35-4 1-phenyl-2,4-dimethyl-4-(α-ethoxy-p-nitrobenzyl)-3,5-dioxopyrazolidine 
• 19933-22-3 1-phenyl-pyrazolidine-3,5-dione 
• 2829-27-8 4-nitro-benzaldehyde phenylhydrazone 
• 934000-74-5 4-(4'-nitrobenzyl)-1-phenyl-3,5-pyrazolidinedione 
• 1296783-90-8 1-phenyl-2'-(4-nitrophenyl)-3,5-dioxo-1,2,3,5-tetrahydrospiropyrazole-4,3'-oxirane 

Relevant academic research and scientific papers

Green synthetic investigation and spectral characterization of some spiro pyrazolidine-based heterocycles with potential biological activity

A green, rapid, and efficient methodology is developed for the synthesis of 1-phenyl-3,5-pyrazolidinedione (3) by the reaction of malonic acid with phenyl hydrazine in the presence of phosphorous oxychloride under solvent-free conditions. The later compou

CHEMISTRY OF THE PYRAZOLIDINES. 26. ALKYLATION OF 4-BENZYLIDEN-1-PHENYL-3,5-DIOXOPYRAZOLIDINES

The reaction of 4-benzyliden-1-phenyl-3,5-dioxopyrazolidines with alkyl halides in the presence of sodium alkoxide gave 1-phenyl-2-alkyl-4-benzyliden- and 1-phenyl-2,4-dialkyl-4-(α-alkoxybenzyl)-3,4-dioxopyrazolines.The structures of these compounds were confirmed by UV, IR, and PMR spectroscopy, and by mass spectrometry.