460095-38-9

Basic information

• Product Name: 4-trimethylsilyl-3-butyn-2-one phenylhydrazone
• Synonyms: 4-trimethylsilyl-3-butyn-2-one phenylhydrazone
• CAS NO: 460095-38-9
• Molecular Weight: 230.385
• Mol File: 460095-38-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-trimethylsilyl-3-butyn-2-one phenylhydrazone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-trimethylsilyl-3-butyn-2-one phenylhydrazone(460095-38-9)
• EPA Substance Registry System: 4-trimethylsilyl-3-butyn-2-one phenylhydrazone(460095-38-9)

Safety Data

• Hazardous Substances Data: 460095-38-9(Hazardous Substances Data)

Upstream product

• 1066-54-2 trimethylsilylacetylene 
• 23183-95-1 1-dimethylphenylsilyl-2-trimethylsilylacetylene 
• 5930-98-3 4-trimethylsilyl-3-butyn-2-one 
• 100-63-0 phenylhydrazine 
• 59-88-1 phenylhydrazine hydrochloride 

Downstream Products

• 1318239-42-7 4-fluoro-3-methyl-1-phenyl-5-(trimethylsilyl)-1H-pyrazole 
• 1447990-49-9 bis(3-methyl-1-phenyl-5-(trimethylsilyl)-1H-pyrazol-4-yl)methanone 

Relevant articles and documents

Regiospecific synthesis of 5-silyl azoles

5-Silylisoxazoles bearing other silyl groups different to the more usual trimethylsilyl have been prepared by condensation of silylalkynones with hydroxylamine hydrochloride. The reaction with hydrazines is more complex and leads to 5-silylpyrazoles or the corresponding hydrazones, which can be cyclized by reaction with electrophiles. This has allowed us to synthesize 5-silylpyrazoles functionalized at C-4 by groups impossible to introduce by electrophilic substitution of the pyrazole nucleus.