4607-63-0

Basic information

• Product Name: Benzeneacetic acid, a-hydroxy-4-(1-methylethyl)-
• CAS NO: 4607-63-0
• Molecular Formula: C11H14O3
• Molecular Weight: 194.23
• Mol File: 4607-63-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzeneacetic acid, a-hydroxy-4-(1-methylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, a-hydroxy-4-(1-methylethyl)-(4607-63-0)
• EPA Substance Registry System: Benzeneacetic acid, a-hydroxy-4-(1-methylethyl)-(4607-63-0)

Safety Data

• Hazardous Substances Data: 4607-63-0(Hazardous Substances Data)

Upstream product

• 51208-83-4 2-(4-isopropylphenyl)-2-oxoacetic acid 
• 91132-18-2 2-hydroxy-2-(4-isopropylphenyl)acetonitrile 
• 98-82-8 Isopropylbenzene 
• 609-09-6 Diethyl ketomalonate 
• 151-50-8 potassium cyanide 
• 122-03-2 (4-isopropylbenzaldehyde) 
• 74-90-8 hydrogen cyanide 
• 75-25-2 Bromoform 

Downstream Products

• 421545-72-4 5-(4-isopropyl-phenyl)-[1,3]dioxolane-2,4-dione 
• 165263-45-6 DL-α-Chlor-p-cumenylessigsaeure 
• 51208-83-4 2-(4-isopropylphenyl)-2-oxoacetic acid 
• 4476-28-2 (4-isopropylphenyl)acetic acid 
• 105401-52-3 methyl 2-hydroxy-2-[4-(propan-2-yl)phenyl] acetate 
• 1206733-80-3 6-bromo-3-(4-isopropylphenyl)-4,5,7-trimethyl-1-benzofuran-2(3H)-one 

Relevant articles and documents

The Synthesis of Chiral α-Aryl α-Hydroxy Carboxylic Acids via RuPHOX-Ru Catalyzed Asymmetric Hydrogenation

A ruthenocenyl phosphino-oxazoline-ruthenium complex (RuPHOX?Ru) catalyzed asymmetric hydrogenation of α-aryl keto acids has been successfully developed, affording the corresponding chiral α-aryl α-hydroxy carboxylic acids in high yields and with up to 97% ee. The reaction could be performed on a gram scale with a relatively low catalyst loading (up to 5000 S/C) and the resulting products can be transformed to several chiral building blocks, biologically active compounds and chiral drugs. (Figure presented.).

CANNABINOID RECEPTOR MODULATOR

A cannabinoid receptor modulator containing a compound represented by Formula (I0) wherein, X is an oxygen atom, etc., R° is an optionally substituted acylamino group, ring A0 is a benzene ring which may further have a substituent in addition to R°, and ring B is an optionally substituted 5-membered heterocycle, or a salt thereof or a prodrug thereof.