46133-05-5Relevant academic research and scientific papers
A dimethacrylate cross-linker cleavable under thermolysis or alkaline hydrolysis conditions: Synthesis, polymerization, and degradation
Elladiou, Marios,Patrickios, Costas S.
supporting information, p. 3135 - 3138 (2016/02/23)
We develop a new platform based on 2,6-pyridinediethanol diesters for introducing polymer degradability under thermolysis or alkaline hydrolysis conditions, with the latter being rare in polymers. Such labile diesters can be cross-linkers, bifunctional initiators and inimers. We demonstrate the power of this platform through the synthesis of the 2,6-pyridinediethanol dimethacrylate cross-linker, its controlled (co)polymerization, and the thermal and hydrolytic cleavage of its (co)polymers.
Cycloalkyl-dione Derivatives And Methods Of Their Use
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Page/Page column 23, (2013/02/28)
The present invention is directed to compounds of formula I: wherein A is n is 0, 1, or 2; m is 0 or 1; R1 is H or C1-6alkyl and R2 is H, C1-6 alkyl, substituted or unsubstituted aryl, or substituted or unsubsti
Compounds - 801
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Page/Page column 78, (2011/04/14)
Spirocyclic amide derivatives of formula I wherein ArCH2CH2NH— represents a β-adrenoceptor binding group, processes for their preparation, pharmaceutical compositions containing them, a process for preparing such pharmaceutical compo
Cyclopentane-1,3-dione: A novel isostere for the carboxylic acid functional group. Application to the design of potent thromboxane (A2) receptor antagonists
Ballatore, Carlo,Soper, James H.,Piscitelli, Francesco,James, Michael,Huang, Longchuan,Atasoylu, Onur,Huryn, Donna M.,Trojanowski, John Q.,Lee, Virginia M.-Y.,Brunden, Kurt R.,Smith, Amos B.
experimental part, p. 6969 - 6983 (2011/12/02)
Cyclopentane-1,3-diones are known to exhibit pKa values typically in the range of carboxylic acids. To explore the potential of the cyclopentane-1,3-dione unit as a carboxylic acid isostere, the physical-chemical properties of representative co
Diphenylmethyl compounds useful as muscarinic receptor antagonists
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Page/Page column 19, (2008/06/13)
This invention provides compounds of formula I: wherein a, b, c, e, m, n, Ar1, R1, R2, R3, R4a, R4b, R5 and R6 are as defined in the specification. The compounds of fo
Synthesis and inhibitory effects op bivalent sialyl Lewis X analogs at preventing cell adhesion
Miyauchi, Hiroshi,Yuri, Masatoshi,Tanaka, Masashi,Kawamura, Nobuko,Hayashi, Masaji
, p. 989 - 992 (2007/10/03)
Several sialyl Lewis X (SLeX) dimers attached to symmetric linkers, 1,3-di(ω-hydroxyalkyl)-benzene, 1,3-di(ω-hydroxyalkoxy)benzene, and 1,3-di(ω-hydroxyalkoxy)cyclohexane, were synthesized and evaluated for their inhibitory activity against adhesion of HL
A New General Synthesis of Polycyclic Aromatic Compounds Based on Enamine Chemistry
Harvey, Ronald G.,Pataki, John,Cortez, Cecilia,Raddo, Pasquale Di,Yang, ChengXi
, p. 1210 - 1217 (2007/10/02)
Alkylation of enamines and enamine salts by benzylic and (β-haloethyl)aryl halides, respectively, followed by acidic cyclodehydration and dehydrogenation provides an efficient synthetic approach to a wide range of polycyclic aromatic compounds of diverse structural types.Specific polycyclic hydrocarbons synthesized by this route include benzo- and benzofluorene, 7H-dibenzo-, 13H-dibenzo-, and 13H-dibenzofluorene, 15H-tribenzofluorene, dibenzochrysene, benzopentaphene, indenofluorene, fluorenofluorene, octahydrodibenzanthracene, dibenzanthracene, octahydrodibenzanthracene, dibenzanthracene, picene, benzopicene, 1H-benzaceanthrylene, and 4H-cyclopentachrysene.This method with appropriate modifications appears to be potentially broader in scope than established traditional methods of polycyclic hydrocarbon synthesis.
