461638-99-3Relevant academic research and scientific papers
Transformation of helical sense of poly(N-propargylamides) controlled by competition between structurally different enantiomeric amino acids
Zhao, Haichao,Sanda, Fumio,Masuda, Toshio
, p. 8888 - 8892 (2004)
Copolymerizations of structurally different chiral amino acid-based N-propargylamides, N-(tert-butoxycarbonyl)-D-alanine-N-propargylamide (DA) with either N-(tert-butoxycarbonyl)-L-valine-N-propargylamide (LV) or N-(tert-butoxycarbonyl)-L-phenylalanine-N-
Optically active amino acid-based polyacetylenes: Effect of tunable helical conformation on infrared emissivity property
Bu, Xiaohai,Zhou, Yuming,Chen, Zhenjie,He, Man,Zhang, Tao
, p. 17 - 24 (2014)
Chiral amino acid-based monosubstituted acetylene monomers [N-tert-butoxy-carbonyl-l-phenylalanine-N′-propargylamide (LP), and N-tert-butoxycarbonyl-l-serine-N′-propargylamide (LS)] were (co)polymerized with rhodium zwitterion catalyst in THF to afford he
Expressed Protein Ligation without Intein
Kratch, Kaci C.,Leeuwon, Sunshine Z.,Liu, Wenshe Ray,Morse, Jared S.,Qiao, Yuchen,Wang, Wesley Wei,Wang, Xiaoyan Aria,Xu, Shiqing,Yu, Ge
supporting information, p. 7047 - 7054 (2020/05/14)
Proteins with a functionalized C-terminus such as a C-terminal thioester are key to the synthesis of larger proteins via expressed protein ligation. They are usually made by recombinant fusion to intein. Although powerful, the intein fusion approach suffe
Synthesis and Reversible Hydration of a Pseudoprotein, a Fully Organic Polymeric Desiccant by Multiple Single-Crystal-to-Single-Crystal Transformations
Mohanrao, Raja,Sureshan, Kana M.
supporting information, p. 12435 - 12439 (2018/09/10)
A diphenylalanine derivative, N3-Phe-Phe-NHCH2CCH, was designed for topochemical azide–alkyne cycloaddition (TAAC) polymerization. This dipeptide adopted β-sheet arrangement as designed, in its crystals, but the azide and alkyne were not fitly aligned for
Chemical probes for competitive profiling of the quorum sensing signal synthase PqsD of Pseudomonas aeruginosa
Prothiwa, Michaela,Szamosvári, Dávid,Glasmacher, Sandra,B?ttcher, Thomas
supporting information, p. 2784 - 2792 (2017/01/09)
The human pathogen Pseudomonas aeruginosa uses the pqs quorum sensing system to coordinate the production of its broad spectrum of virulence factors to facilitate colonization and infection of its host. Hereby, the enzyme PqsD is a virulence related quoru
A magnetoclick imidazolidinone nanocatalyst for asymmetric 1,3-dipolar cycloadditions
Pagoti, Sreenivasarao,Dutta, Debasish,Dash, Jyotirmayee
supporting information, p. 3532 - 3538 (2014/01/06)
A 1,3-dipolar azide-alkyne cycloaddition has been used to prepare a magnetic nanoparticle immobilized MacMillan catalyst that catalyzes the enantioselective 1,3-dipolar cycloaddition between nitrones and α,β-unsaturated aldehydes. The catalyst can be recovered and recycled for five consecutive runs without any significant loss in yields and diastereo- and enantioselectivities of the isoxazolidines. Copyright
IAP ANTAGONISTS
-
Paragraph 00286, (2014/01/09)
There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
Using click chemistry to access mono- and ditopic β-cyclodextrin hosts substituted by chiral amino acids
Tran, Diem Ngan,Blaszkiewicz, Claire,Menuel, Stéphane,Roucoux, Alain,Philippot, Karine,Hapiot, Frédéric,Monflier, Eric
experimental part, p. 210 - 218 (2011/03/18)
A wide range of chiral mono- and ditopic cyclodextrin-based receptors have been synthesized by CuI-catalyzed azide-alkyne cycloaddition starting from mono-6-azido-β-cyclodextrin and chiral amino acids. Of interest, microwaves proved very efficient to acce
Gold-catalysed synthesis of amino acid-derived 2,5-disubstituted oxazoles
Paradise, Christopher L.,Sarkar, Pooja R.,Razzak, Mina,De Brabander, Jef K.
supporting information; experimental part, p. 4017 - 4020 (2011/07/29)
Amino acid-derived propargylic amides are cyclised in a one-pot, Au(iii)-catalysed operation to yield 5-bromomethyl oxazoles. These compounds are further elaborated to bis-heterocycles, dipeptide mimics and more.
CuAAC macrocyclization: High intramolecular selectivity through the use of copper-tris(triazole) ligand complexes
Chouhan, Gagan,James, Keith
supporting information; experimental part, p. 2754 - 2757 (2011/06/26)
A range of multivalent heteroaryl ligands, copper sources, and solvent systems have been investigated for use in CuAAC-mediated macrocyclization reactions. These studies have revealed the key factors governing selectivity for macrocyclization versus dimerization and identified a simple but specific set of reaction conditions capable of efficiently generating a diverse series of drug-like macrocycles at modest dilution in up to 95% yield.
