461677-86-1

Upstream product

• 3377-71-7 N-benzylindole 
• 461677-71-4 1-benzyl-3-diazo-1,3-dihydro-2H-indol-2-one 
• 91-56-5 indole-2,3-dione 
• 120-72-9 indole 
• 33333-60-7 3-hydroxy-3-indolyl-2-oxindole 
• 100-39-0 benzyl bromide 
• 3265-29-0 3-diazo-indolin-2-one 

Downstream Products

• 860653-32-3 1,1'-dibenzyl-2-(tert-butyldimethylsiloxy)-1H,1'H-[3,3']biindolyl 
• 371252-55-0 2,2'-((3S,3'S)-1,1'-dibenzyl-2,2'-dioxo-[3,3'-biindoline]-3,3'-diyl)diacetaldehyde 
• 247061-40-1 (3S,3'S)-1,1'-dibenzyl-3,3'-bis-(2-hydroxyethyl)-[3,3'-biindoline]-2,2'-dione 

Relevant academic research and scientific papers

Organocatalytic Asymmetric Synthesis of Spiro-Bridged and Spiro-Fused Heterocyclic Compounds Containing Chromane, Indole, and Oxindole Moieties

Following the reactivity inversion strategy, two different two-step sequences were designed and successfully applied to the asymmetric synthesis of spiro-bridged and spiro-fused heterocyclic compounds, which combined chromane, indole, and oxindole, three

Catalytic Enantioselective Decarboxylative Allylations of a Mixture of Allyl Carbonates and Allyl Esters: Total Synthesis of (-)- and (+)-Folicanthine

A highly enantioselective decarboxylative allylation of a mixture of enol carbonates and allyl esters has been achieved. The strategic viability of this methodology has been demonstrated through the total synthesis of cyclotryptamine alkaloids (-)- and (+)-folicanthine (1 a) and the formal total synthesis of (-)-chimonanthine (1 b), (+)-calycanthine (1 c), and (-)-ditryptophenaline (1 d).

Diastereoselective synthesis of strained spiro-cyclopropanooxindoles from cyclic diazoamides

Reaction of cyclic diazoamides and cyclic olefins or heteroaromatic systems using copper(I) triflate as a catalyst furnished a variety of strained spiro-cyclopropanooxindoles in a diastereoselective manner under mild reaction conditions. The effect of copper(I) triflate and rhodium(II) acetate catalysts on the cyclopropanation was also studied.

First example of regiospecific intermolecular C-H insertion reactions of cyclic rhodium carbenoids: Novel synthesis of 3-indol-3′-yloxindoles

Facile regiospecific intermolecular C-H insertion reactions of cyclic rhodium carbenoids have been achieved using diazo carbonyl compounds 1 and indole or N-substituted indoles to afford 1,3-dihydro-1′H-[3,3′]biindolyl-2-ones, 3a-o in an excellent yield.