4620-34-2

Usage

Uses

Used in Pharmaceutical Industry:
1,2,3,4-Tetrahydro-quinoline-2-carboxylic acid ethyl ester is used as a pharmaceutical intermediate for the synthesis of various drugs. Its unique structure and properties make it a valuable building block in the development of new medications with potential therapeutic benefits.
Used in Chemical Industry:
In the chemical industry, 1,2,3,4-tetrahydro-quinoline-2-carboxylic acid ethyl ester can be utilized as a reagent or catalyst in various chemical reactions. Its carboxylic acid and ethyl ester groups may facilitate specific transformations or enhance the efficiency of certain processes.

InChI:InChI=1/C12H15NO2/c1-2-15-12(14)11-8-7-9-5-3-4-6-10(9)13-11/h3-6,11,13H,2,7-8H2,1H3

Upstream product

• 46185-24-4 1,2,3,4-tetrahydroquinoline-2-carboxylic acid 
• 64-17-5 ethanol 
• 93-10-7 quinoline-2-carboxylic acid 
• 4491-33-2 ethyl quinoline-2-carboxylate 

Downstream Products

• 1034771-03-3 Ethyl 1-benzyl-1,2,3,4-tetrahydroquinoline-2-carboxylate 
• 1018826-32-8 tert-butyl 2-((1-(3,4-dichlorophenylsulfonyl)-1,2,3,4-tetrahydroquinolin-2-yl)methoxy)-acetate 
• 1018826-33-9 2-((1-(3,4-dichlorophenylsulfonyl)-1,2,3,4-tetrahydroquinolin-2-yl)-methoxy)acetic acid 
• 1018826-31-7 [1-(3,4-dichloro-phenylsulfonyl)-1,2,3,4-tetrahydro-quinolin-2-yl]-methanol 

Relevant academic research and scientific papers

Enantioselective Synthesis of 2-Functionalized Tetrahydroquinolines through Biomimetic Reduction

Biomimetic asymmetric reduction of 2-functionalized quinolines has been successfully developed with the chiral and regenerable NAD(P)H model CYNAM in the presence of transfer catalyst simple achiral phosphoric acids, providing the chiral 2-functionalized

ANTAGONISTS OF THE TRPV1 RECEPTOR AND USES THEREOF

The present application is directed to compounds that are TRPV1 antagonists and have formula (I) wherein variables Ar1, L1, R1, R2, R3, R4, R5, Y1, Y2, and Y3, are as defined in the description, which are useful for treating disorders caused by or exacerbated by vanilloid receptor activity.

7-fused 2-(piperazinoalkyl) indole derivatives, intermediates and compositions thereof

Pharmacologically active compounds having anti-allergic properties corresponding to the formula I STR1 which can be mono- or disubstituted in the phenyl ring and their acid addition salts and/or S-mono- or dioxides of sulfur-containing compounds of the formula I are described, together with processes and intermediates for their preparation.

Reduction of Quinolinecarboxylic Acids by Raney Alloy

The heterocyclic nucleus in quinolinecarboxylic acids is reduced by Raney alloy (nickel-aluminium) in alkaline media to give 1,2,3,4-tetrahydro-2-,3-,4-,5-,6-, and 8-quinolinecarboxylic acids and 8-methyl-5-quinolinecarboxylic acid and their ethyl esters.