4491-33-2

Basic information

• Product Name: ethyl quinoline-2-carboxylate
• Synonyms: ethyl quinoline-2-carboxylate;Ethyl quinoline-2-carboxylic acid;2-Quinolinecarboxylic acid, ethyl ester;2-Quinoline carbocylic acid ethyl ester
• CAS NO: 4491-33-2
• Molecular Formula: C₁₂H₁₁NO₂
• Molecular Weight: 201.224
• EINECS: -0
• Mol File: 4491-33-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 30-33 °C(Solv: ethyl ether (60-29-7))
• Boiling Point: 333.9 °C at 760 mmHg
• Flash Point: 155.8 °C
• Appearance: /
• Density: 1.175 g/cm³
• Vapor Pressure: 1.95E-05mmHg at 25°C
• Refractive Index: 1.643
• Storage Temp.: 2-8°C
• PKA: 2.07±0.40(Predicted)
• CAS DataBase Reference: ethyl quinoline-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl quinoline-2-carboxylate(4491-33-2)
• EPA Substance Registry System: ethyl quinoline-2-carboxylate(4491-33-2)

Safety Data

• Hazardous Substances Data: 4491-33-2(Hazardous Substances Data)

Usage

Chemical Properties

yellow powder

InChI:InChI=1/C12H11NO2/c1-2-8-7-9-5-3-4-6-10(9)13-11(8)12(14)15/h3-7H,2H2,1H3,(H,14,15)

Upstream product

• 617-35-6 2-oxo-propionic acid ethyl ester 
• 91-22-5 quinoline 
• 75-00-3 chloroethane 
• 124-38-9 carbon dioxide 
• 612-62-4 2-Chloroquinoline 

Downstream Products

• 113569-39-4 quinoline-2-carboxylic acid-(2-benzo[1,3]dioxol-5-yl-1-methyl-ethylamide) 
• 108237-03-2 3-[2]quinolyl-3-oxo-2-phenyl-propionitrile 
• 30836-61-4 1,1-diphenyl-1-(2-quinolyl)methanol 
• 1011-47-8 1-quinolin-2-yl-ethanone 
• 96057-59-9 ethyl 3-oxo-3-(quinolin-2-yl)propanoate 
• 1780-17-2 quinolin-2-ylmethanol 
• 5382-44-5 quinoline-2-carboxylic acid hydrazide 
• 37137-42-1 N-hydroxy-2-quinolinecarboxamide 
• 1026852-20-9 4-Hydroxy-3-(3-oxo-3-quinolin-2-yl-propionyl)-benzoic acid ethyl ester 
• 1027523-32-5 5-Bromo-2-hydroxy-3-(3-oxo-3-quinolin-2-yl-propionyl)-benzoic acid ethyl ester 
• 903178-41-6 N-benzyl-2-(quinolin-2-ylcarbonyl)hydrazincarbothioamide 
• 676154-53-3 4-benzyl-5-(quinolin-2-yl)-4H-1,2,4-triazol-3-thiol 
• 1383550-96-6 4-benzyl-2-(morpholin-4-ylmethyl)-5-(quinolin-2-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 1383551-03-8 3-[(4-phenylpiperazin-1-yl)methyl]-5-(quinolin-2-yl)-1,3,4-oxadiazol-2(3H)-thione 

Relevant articles and documents

Reductive electrochemical carboxylation in context with quantum chemical calculations

-

Electrochemical Carboxylation of Some Heteroaromatic Compounds

Thirty heteroaromatic compounds have been investigated by cyclic voltammetry (CV) and/or preparative scale electrolysis (PSE) in the absence and presence of carbon dioxide.The rate constants of dehalogenation of the primarily formed anion radical of halogenated heterocycles were estimated from cyclic voltammetric data; these data indicated that carboxylation without loss of chlorine is possible under cyclic voltammetric conditions when the rate constant of cleavage is less than about 104 s-1.PSE confirmed that such halogenated heterocycles may be reductively carboxylated without loss of halogen.In the competition between cleavage and carboxylation low temperatures favour the latter reaction.