462102-47-2Relevant academic research and scientific papers
Easily accessible chiral P,N-bidentate aryl phosphites, their complexation and application in enantioselective allylic alkylation, sulfonylation and hydrosilylation
Gavrilov, Konstantin N.,Bondarev, Oleg G.,Lebedev, Roman V.,Shiryaev, Alexei A.,Lyubimov, Sergey E.,Polosukhin, Alexei I.,Grintselev-Knyazev, Gennady V.,Lyssenko, Konstantin A.,Moiseev, Sergey K.,Ikonnikov, Nikolay S.,Kalinin, Valery N.,Davankov, Vladim A.,Korostylev, Andrei V.,Gais, Hans-Joachim
, p. 1367 - 1376 (2007/10/03)
New chiral P,N-hybrid aryl phosphites have been obtained by one-step phosphorylation of amino and imino alcohols. Complexation of the new ligands with [Rh(CO)2Cl]2, [Pd(COD)Cl2] and [Pd(allyl)Cl]2 was found to give chelate complexes [Rh(CO)Cl(Bη2-pn∩N)], [PdCl2(Bη2-pn∩N)] and [Pd-(allyl) (Bη2-pn∩N)]+Cl-, respectively. With these new P,N-ligands, up to 82percent ee enantioselectivity was achieved in the Pd-catalysed alkylation of ethyl 3-penten-2-yl carbonate with dimethyl malonate, up to 80percent ee in the Pd-catalysed sulfonylation of methyl 3-penten-2-yl carbonate with sodium p -toluenesulfinate, and up to 50percent ee in the Rh-catalysed hydrosilylation of acetophenone with diphenylsilane. ? Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002.
