46274-23-1

Upstream product

• 92367-72-1 (3,4-dimethoxy-5-methylphenyl)acetonitrile 
• 3327-75-1 1,2-Dimethoxy-4,6-bis-cyanmethyl-benzol 
• 37987-18-1 4-Hydroxy-3-methoxy-5-methyl-benzylalkohol 
• 3153-97-7 2-methoxy-4,6-bishydroxymethyl phenol 
• 93686-97-6 3,4-Dimethoxy-5-methyl-benzylchlorid 
• 3154-00-5 1,2-Dimethoxy-4,6-bis-chlormethyl-benzol 
• 80547-79-1 (3,4-dimethoxy-5-methylphenyl)methanol 
• 90-05-1 2-methoxy-phenol 
• 32263-14-2 4-hydroxy-3-methoxy-5-methylbenzaldehyde 
• 28276-04-2 3-(chloromethyl)-4-hydroxy-5-methoxybenzaldehyde 
• 87743-10-0 3-((dimethylamino)methyl)-4-hydroxy-5-methoxybenzaldehyde 
• 121-33-5 vanillin 
• 80547-80-4 3,4-dimethoxy-5-methylbenzaldehyde 
• 3153-98-8 3,4,5-trimethoxybenzyl alcohol 

Downstream Products

• 104114-01-4 N-[2-(3,4-Dimethoxy-5-methyl-phenyl)-ethyl]-2-hydroxy-2-(4-methoxy-phenyl)-acetamide 
• 104114-04-7 N-[2-(3,4-dimethoxy-5-methylphenyl)ethyl]-2-(4'-methoxyphenyl)-2-hydroxyethylamine 
• 72912-58-4 1-(4'-hydroxyphenyl)-7,8-dihydroxy-6-chloro-9-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride 
• 72912-36-8 9-methyl-7,8-dihydroxy-1-(4'-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide 
• 104114-07-0 7,8-Dimethoxy-1-(4-methoxy-phenyl)-9-methyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine 

Relevant academic research and scientific papers

Tetrahydrocoptisine derivative and applications thereof

The present invention relates to a compound as shown in a formula (VII), a preparation method and applications thereof in medicines. In particular, the present invention relates to a derivative of the compound as shown in the formula (VII), a preparation method, and the applications of the derivative used as a therapeutic agent in prevention and treatment of hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, hepatic steatosis, II-type diabetes, hyperglycemia, obesity or insulin resistance syndrome and metabolic syndrome. The compound disclosed by the present invention can also reduce total cholesterol, LDL-cholesterol and triglyceride, and increases expression of a liver LDL receptor and decreases expression of PCSK9.

Benz-tetrasubstituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines

A group of 6,9-disubstituted-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines have dopaminergic activity. Examples of leading species of the invention are 6,9-dichloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine and 6,9-dichloro-7,8-dihydroxy-1-(p-hydroxy-phenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine in the form of an acid addition salt.