46320-17-6

Upstream product

• 3349-64-2 1-tetralone oxime 
• 67-56-1 methanol 
• 67857-97-0 4-(2-nitrophenyl)-n-butyric acid 
• 5600-62-4 4-(4-nitrophenyl)butanoic acid 
• 4424-80-0 2,3,4,5-tetrahydro-1H-1-benzo[b]azepin-2-one 
• 1821-12-1 4-Phenylbutyric acid 
• 22824-20-0 4(2-nitrophenyl)butanoic acid methyl ester 

Downstream Products

• 113849-34-6 methyl 4-phenyl>butyrate 
• 1070892-36-2 4-[2-(3-bromo-4-chloro-benzoylamino)-phenyl]-butyric acid methyl ester 
• 1070892-40-8 4-(2-[(3-bromo-4-chloro-benzoyl)-methyl-amino]-phenyl)-butyric acid 
• 1070892-37-3 4-{2-[(3-bromo-4-chloro-benzoyl)-methyl-amino]-phenyl}-butyric acid methyl ester 
• 1070892-41-9 4-{2-[(3-bromo-4-chloro-benzoyl)-methyl-amino]-phenyl}-butyric acid tert-butyl ester 
• 1070890-16-2 4-(2-{[4-chloro-3-(6-chloro-4-methyl-pyridin-3-yl)-benzoyl]-methyl-amino}-phenyl)-butyric acid methyl ester 
• 1070890-20-8 4-(2-{[4-chloro-3-(6-chloro-4-methyl-pyridin-3-yl)-benzoyl]-methyl-amino}-phenyl)-butyric acid 
• 1070892-38-4 4-(2-{[4-chloro-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzoyl]-methyl-amino}-phenyl)-butyric acid methyl ester 
• 1070892-42-0 4-(2-{[4-chloro-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzoyl]-methyl-amino}-phenyl)-butyric acid tert-butyl ester 
• 1070890-24-2 4-(2-{[4-chloro-3-(3-cyano-quinolin-2-yl)-benzoyl]-methyl-amino}-phenyl)-butyric acid 
• 1070892-43-1 4-(2-{[4-chloro-3-(3-cyano-quinolin-2-yl)-benzoyl]-methyl-amino}-phenyl)-butyric acid tert-butyl ester 
• 943345-27-5 4-(2-{[5-(4-methoxyphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}phenyl)butanoic acid methyl ester 
• 402473-36-3 4-[2-[2-(1-naphthyl)propanoylamino]phenyl]butanoic acid methyl ester 

Relevant academic research and scientific papers

Synthesis method of benzocaprolactam

The invention discloses a synthesis method of benzocaprolactam. The synthesis method comprises the following steps: S1, using o-nitrotoluene as a raw material, and carrying out a condensation reactionon the o-nitrotoluene and an acrylate under catalysis o

Novel, Cyclically Substituted Furopyrimidine Derivatives and Use Thereof

The present application relates to novel, cyclically substituted furopyrimidine derivatives, methods for their production, their use for the treatment and/or prophylaxis of diseases and their use for the production of medicinal products for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular diseases.

Histone deacetylase inhibitors

This invention relates to novel Histone deacetylases inhibitors. Also disclosed is a method for treating mucositis or cancer with these inhibitors.

GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO

GnRH receptor antagonists are disclosed which have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure, wherein R1a, R1b, R1c, R1d, R2, R2a, and A are as defined herein, including stereoisomers, esters, solvates and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof.

Carboxylic acid derivatives, process for producing the same and drugs containing the same as the active ingredient

A carboxylic acid derivative of formula (1) wherein R1 is COOH, COOR6 etc.; A is alkylene etc.; R2 is alkyl, alkenyl, alkynyl etc.; B is carbocyclic ring or heterocyclic ring; R4 is alkyl, cycloalkyl etc.; Rsup

1-Aryl-3-(2-chloroethyl) ureas: Synthesis and in vitro assay as potential anticancer agents

1-Aryl-3-(2-chlorethyl) ureas and 1-aryl-3-nitrose-3-(2-chloroethyl) ureas, derived from 4-phenylbutyric acid and alkylanillines, were synthesized and their cytotoxicity was evaluated on human adenocarcinoma cells in vitro. Methyl 4-[p-[3-(2-chloroethyl)ureido]-phenyl]butyrate, 4-methyl [3-(2-chloroethyl)ureido]benzene, and 4-butyl[3-(2-chloroethyl)ureido]benzene were found to be at least as cytotoxic as 4-[p-[bis-(2-chloroethyl)amino]phenyl]butyric acid (chlorambucil), while their N-nitrose derivatives were inactive.