46329-82-2

Basic information

• Product Name: 5,5-dimethyl-2-(1',1'-dimethyl-2'-hydroxyethyl)-4-hydroxy-1,3-dioxane
• CAS NO: 46329-82-2
• Molecular Weight: 204.266
• Mol File: 46329-82-2.mol
• Article Data: 1

Chemical Properties

• Melting Point: 88-89.5 °C(Solv: ethyl ether (60-29-7))
• Boiling Point: 306.7±32.0 °C(Predicted)
• Density: 1.088±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 5,5-dimethyl-2-(1',1'-dimethyl-2'-hydroxyethyl)-4-hydroxy-1,3-dioxane(CAS DataBase Reference)
• NIST Chemistry Reference: 5,5-dimethyl-2-(1',1'-dimethyl-2'-hydroxyethyl)-4-hydroxy-1,3-dioxane(46329-82-2)
• EPA Substance Registry System: 5,5-dimethyl-2-(1',1'-dimethyl-2'-hydroxyethyl)-4-hydroxy-1,3-dioxane(46329-82-2)

Safety Data

• Hazardous Substances Data: 46329-82-2(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 78-84-2 isobutyraldehyde 

Downstream Products

• 7299-86-7 2-(5,5-dimethyl[1,3]dioxane-2-yl)-2-methylpropane-1-ol 
• 126-30-7 2,2-Dimethyl-1,3-propanediol 
• 1115-20-4 2,2-dimethyl-3-hydroxy-propyl 2,2-dimethyl-3-hydroxypropionate 
• 597-31-9 2,2-dimethyl-3-hydroxypropionaldehyde 

Relevant articles and documents

Efficient biocatalytic synthesis of (R)-pantolactone

Screening for stereoselective cyanohydrin synthesis in 96-well plates was employed in the development of an efficient, pH-stable hydroxynitrile lyase for the conversion of sterically hindered aliphatic aldehydes. Site-saturation mutagenesis (SSM) resulted in a powerful catalyst for the stereoselective conversion of hydroxypivalaldehyde and pivalaldehyde to their corresponding (R)-cyanohydrins (ee >97%) which are used as chiral building blocks (e.g., for pantothenic acid production). Furthermore, redesigning the PaHNL5 gene and improving its expression by Pichia pastoris with the help of a new P AOX1 promoter variant and the helper protein PDI (protein disulfide isomerase) led to elevated amounts of today's most efficient biocatalyst for vitamin B5 synthesis.