463303-85-7

Upstream product

• 86-98-6 4,7-dichloroquinoline 
• 109-89-7 diethylamine 
• 243989-41-5 {3-amino-5-[(7-chloro-4-quinolyl)amino]phenyl}methanol 
• 28150-15-4 3,5-diaminobenzyl alcohol dihydrochloride 

Downstream Products

• 1020167-14-9 C₂₀H₂₂ClN₃O 

Relevant academic research and scientific papers

Synthesis and antimalarial activity of new analogues of amodiaquine

In order to determine the real significance of the 4′-phenolic group in the antimalarial activity and/or cytotoxicity of amodiaquine (AQ), analogues for which this functionality was shifted or modified were synthesized. Good in vitro antimalarial activity

"One-pot" synthesis and antimalarial activity of formamidine derivatives of 4-anilinoquinoline

Amodiaquine (AQ) is an antimalarial which is effective against chloroquino-resistant strains of Plasmodium falciparum but whose clinical use is severely restricted because of associated hepatotoxicity and agranulocytosis. "One-pot" synthesis of formamidin