463349-85-1 Usage
Uses
Used in Pharmaceutical Synthesis:
(S)-Methyl 2-((tert-butoxycarbonyl)amino)-2-((1R,4S)-4-hydroxycyclohexyl)acetate is used as a building block in the pharmaceutical industry for the synthesis of compounds targeting neurological disorders, cancer, and infectious diseases. Its unique structure allows for the development of potential therapeutic agents that can address these health concerns.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (S)-Methyl 2-((tert-butoxycarbonyl)amino)-2-((1R,4S)-4-hydroxycyclohexyl)acetate is used as a key component in the study and development of new bioactive molecules. Its properties and reactivity contribute to the advancement of drug discovery and design.
Safety and Handling:
It is crucial to handle and store (S)-Methyl 2-((tert-butoxycarbonyl)amino)-2-((1R,4S)-4-hydroxycyclohexyl)acetate with care due to its potential health and environmental risks if mismanaged. Proper safety measures should be taken to minimize any risks associated with its use in research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 463349-85-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,6,3,3,4 and 9 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 463349-85:
(8*4)+(7*6)+(6*3)+(5*3)+(4*4)+(3*9)+(2*8)+(1*5)=171
171 % 10 = 1
So 463349-85-1 is a valid CAS Registry Number.
463349-85-1Relevant academic research and scientific papers
INHIBITORS OF IAP
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Page/Page column 48, (2008/06/13)
The invention provides novel inhibitors of IAP that are useful as therapeutic agents for treating malignancies where the compounds have the general formula (I): wherein Q, X1, X2, Y, Z1, Z2, Z3, Z4, R1, R2, R3, R3', R4, R4', R5, R6, R6' and n are as described herein.
4-Amino cyclohexylglycine analogues as potent dipeptidyl peptidase IV inhibitors
Parmee, Emma R.,He, Jiafang,Mastracchio, Anthony,Edmondson, Scott D.,Colwell, Larry,Eiermann, George,Feeney, William P.,Habulihaz, Bahanu,He, Huaibing,Kilburn, Ruth,Leiting, Barbara,Lyons, Kathryn,Marsilio, Frank,Patel, Reshma A.,Petrov, Aleksandr,Di Salvo, Jerry,Wu, Joseph K.,Thornberry, Nancy A.,Weber, Ann E.
, p. 43 - 46 (2007/10/03)
Substituted 4-amino cyclohexylglycine analogues were evaluated for DP-IV inhibitory properties. Bis-sulfonamide 15e was an extremely potent 2.6 nM inhibitor of the enzyme with excellent selectivity over all counterscreens. 2,4-Difluorobenzenesulfonamide 1
FUSED INDOLES AS DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES
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Page 27, (2008/06/13)
The present invention is directed to fused indole derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is in
