464-99-3Relevant articles and documents
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Jolad,S.D.,Steelink,C.
, p. 1367 - 1369 (1969)
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Studies on reaction of 2-bromo-3-ketotriterpenoids: Part IV - Debromination and dehydrobromination of 2α-bromo and 2,2-dibromo derivatives of lupanone and methyl dihydrobetulonate
Pradhan, Bhim Prasad,Ghosh, Pranab
, p. 73 - 75 (2007/10/02)
2α-bromolupanone/methyl 2α-dibromodihydrobetulonate (1/1') and 2,2-dibromolupanone/methyl 2,2-dibromodihydrobetulonate (2/2') on refluxing with dimethylaniline (DMA) for 6 hr afford lupanone/methyl dihydrobetulonate (3/3') whereas 6 hr reflux of 1/1' and 2/2' with LiBr in dimethylformamide (DMF) furnish lup-1(2)-en-3-one/28-carbomethoxylup-1(2)-en-3-one (4/4') and 2-bromolup-1(2)-en-3-one/2-bromo-28-carbomethoxylup-1(2)-en-3-one (5/5'), respectively.On the other hand Wolff-Kishner reduction of 1/2 results in the formation of lupane (6).
HOMOGENEOUS HYDROGENATION AND DEUTERATION OF PENTACYCLIC TRITERPENOIDS: DOUBLE BONDS IN SIDE-CHAINS
Protiva, Jiri,Lepsa, Ludek,Klinotova, Eva,Klinot, Jiri,Krecek, Vaclav,Vystrcil, Alois
, p. 2734 - 2741 (2007/10/02)
The reduction of terminal double bonds in the side chains on the rings A and E of pentacyclic triterpenoids by means of tris(triphenylphosphine)rhodium chloride permits selective reduction of dienes and labelling with deuterium with a low scattering.The effect of the amount of the catalyst and the solvent used on the rate of reduction was studied in the case of 3β,28-diacetylbetulin.
