3186-72-9Relevant articles and documents
Denomination of 2-bromo-3-keto triterpenoids using N,N-dimethylaniline
Ghosh, Pranab,Chakraborty, Prasanta
experimental part, p. 1037 - 1039 (2012/04/04)
Reflux of 2α-bromo/2,2-dibromolupanone (1/1a), methyl 2α-bromo/2,2-dibromodihydrobetulonate (2/2a) and 2/4α-bromofriedelin (3/3a) with N,N-dimethylaniline (DMA) resulted in the formation of lupanone, methyl dihydrobetulonate and friedelin, respectively in very good yields. The products have been characterized by spectroscopic analysis [IR, NMR ( 1H and 13C) and MS] and optical rotation as well as by comparison with the data reported in literature.
Studies on reactions of 2-bromo-3-ketotriterpenoids: Part III - Reduction of 2α-bromo and 2,2-dibromo derivatives of lupanone and methyl dihydrobetulonate with lithium aluminium hydride and sodium borohydride
Pradhan, B P,Ghosh, Pranab
, p. 1178 - 1180 (2007/10/02)
Reduction of methyl 2α-bromodihydrobetulonate/2α-bromolupanone (1/2) and methyl 2,2-dibromodihydrobetulonate/2,2-dibromolupanone (1a/2a) with LAH at room temperature results in the formation of methyl 2α-bromo-3β-hydroxydihydrobetulonate/2α-bromo-3β-hydroxylupane (3/4), methyl dihydrobetulinate/lupanol (3b,4b) and methyl 2α-bromo dihydrobetulonate/2α-bromolupanone (1/2), methyl dihydrobetulinate/lupanol (3b/4b), lupan-2β-3β-diol (5)(from 2a) respectively, while the reduction of 1/2 and 1a/2a with NaBH4 affords 3/4, 3b/4b and methyl dihydrobetulonate/lupanone (1b/2b), 3b/4b respectively.
The synthesis of nor- and bisnorlupanes
Wahhab, Amal,Ottosen, Margaret,Bachelor, Frank W.
, p. 570 - 577 (2007/10/02)
In course of our studies on geochemical biomarkers we required a series of lupane standards.We report here an efficient synthesis of lupane (1) in three steps from betulin (3) in an overall yield of 47.2 percent. 17β(H)-28-Norlupane (2) was obtained in 90
