46407-88-9Relevant academic research and scientific papers
Design, synthesis and biological evaluation of 5-amino-1H-pyrazole-4- carboxamide derivatives as potential antitumor agents
Yang, Baowei,Liu, Wukun,Mei, Yicheng,Huang, Dandan,Qian, Hai,Huang, Wenlong,Gust, Ronald
, p. 749 - 755 (2014/07/07)
Adenosine deaminase (ADA) inhibitors have been found to have antitumor activities. Here, thirteen potential adenosine deaminase inhibitors 5-amino-1H-pyrazole-4-carboxamide derivatives were designed, synthesized and screened for antitumor activities. Comp
One-pot synthesis of tetrasubstituted pyrazoles - Proof of regiochemistry
Hanefeld, Ulf,Rees, Charles W.,White, Andrew J. P.,Williams, David J.
, p. 1545 - 1552 (2007/10/03)
1-Alkyl-5-amino-3-aryl-4-cyanopyrazoles, useful intermediates for fused heterocyclic systems, are synthesised by a one-pot three-step procedure from acid chlorides, malononitrile and alkylhydrazines. The regiochemistry of the hydrazine incorporation was p
Electrolytic Oxidation of Ketones in a Methanolic Solution of NaCN in the Presence of Catalytic Amounts of KI
Okimoto, Mitsuhiro,Chiba, Toshiro
, p. 6194 - 6197 (2007/10/02)
The indirect electrolytic oxidation of ketones (1) in methanolic sodium cyanide was studied using iodide ion as a mediator.The product and the reactivity of ketone were dependent on the nature of the alkyl groups attached to the carbonyl group.Thus, 2-alk
