4643-36-1 Usage
General Description
N-Methyl-1-naphthylamine hydrochloride is a chemical compound that is commonly used as a reagent in the synthesis of various organic compounds. It is a salt form of N-methyl-1-naphthylamine, which is an aromatic amine. N-METHYL-1-NAPHTHYLAMINE HYDROCHLORIDE is often used in the pharmaceutical and chemical industries as an intermediate in the production of dyes and other organic substances. It is also used as a corrosion inhibitor in the rubber and petroleum industries. However, it is important to handle this compound with care as it can be toxic and hazardous if not used properly.
Check Digit Verification of cas no
The CAS Registry Mumber 4643-36-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,6,4 and 3 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4643-36:
(6*4)+(5*6)+(4*4)+(3*3)+(2*3)+(1*6)=91
91 % 10 = 1
So 4643-36-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H11N.ClH/c1-12-11-8-4-6-9-5-2-3-7-10(9)11;/h2-8,12H,1H3;1H
4643-36-1Relevant articles and documents
N-Monomethylation of Aromatic Amines with Methanol via PNHP-Pincer Ru Catalysts
Ogata, Osamu,Nara, Hideki,Fujiwhara, Mitsuhiko,Matsumura, Kazuhiko,Kayaki, Yoshihito
supporting information, p. 3866 - 3870 (2018/07/25)
The use of methanol for the selective methylation of aromatic amines with RuHCl(CO)(PNHP) (PNHP = bis(2-diphenylphosphinoethyl)amine) is reported. Various aromatic amines were transformed into their corresponding monomethylated secondary amines in high yields at 150 °C with a very low catalyst loading (0.02-0.1 mol %) in the presence of KOtBu (20-60 mol %). The catalyst precursor, RuHCl(CO)(PNHP), was converted to [RuH(CO)2(PNHP)]+ under the catalytic conditions and also serves as a highly effective catalyst. The robustness of this catalyst contributes to its outstanding catalytic activity, even under reaction conditions, in which CO is liberated from methanol.