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Bicyclo[2.2.1]heptane-2-methanol, 2-hydroxy-3,3-dimethyl-, also known as 2-hydroxy-3,3-dimethylbicyclo[2.2.1]heptane, is an organic compound with the molecular formula C9H16O. It is a cyclic alcohol with a bicyclic structure, consisting of two carbon rings fused together in a 2.2.1 configuration. The compound features a hydroxyl group (-OH) at the 2-position, and two methyl groups (-CH3) at the 3-position of the bicyclic structure. This chemical is primarily used as a synthetic intermediate in the production of various pharmaceuticals, agrochemicals, and other specialty chemicals. Due to its unique structure and reactivity, it has potential applications in the synthesis of complex organic molecules and as a chiral building block in asymmetric synthesis.

466-12-6

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466-12-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 466-12-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,6 and 6 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 466-12:
(5*4)+(4*6)+(3*6)+(2*1)+(1*2)=66
66 % 10 = 6
So 466-12-6 is a valid CAS Registry Number.

466-12-6Relevant academic research and scientific papers

NaY zeolite as host for the selective heterogeneous oxidation of silanes and olefins with hydrogen peroxide catalyzed by methyltrioxorhenium

Adam, Waldemar,Saha-Moeller, Chantu R.,Weichold, Oliver

, p. 2897 - 2899 (2007/10/03)

The methyltrioxorhenium(MTO)-catalyzed oxidation of silanes to silanols and the epoxidation of various olefins by aqueous 85% H2O2 proceed in high yields and excellent product selectivities (no disiloxanes, diols) in the presence of the zeolite NaY. The oxidative species is located inside the 12- A supercages. This prevents the bimolecular condensation of the silanol to disiloxane by steric means and the Lewis-acid assisted hydrolysis of the epoxide to the diol.

Electrochemical Oxidation of Polycyclic Cyclopropanes and Camphene. Novel Synthesis of exo-5,5-Dimethyl-6-methylenebicycloheptan-2-ol (Nojigiku Alcohol)

Uchida, Toshikazu,Matsubara, Yoshiharu,Nishiguchi, Ikuzo,Hirashima, Tsuneaki,Ohnishi, Takashi,Kanehira, Koichi

, p. 2938 - 2943 (2007/10/02)

Anodic oxidation of tricyclene (1a) in acetic acid containing triethylamine, followed by hydrolysis, provides a facile and efficient synthesis of exo-5,5-dimethyl-6-methylenebicycloheptan-2-ol (2a), named "nojigiku alcohol", which was isolated from the essential oil of chrysanthemum japonese.Furthermore, a method for large-scale production of 2a starting from the readily available impure starting tricyclene (1a) has been developed by appropriate selection of reaction conditions.Similar electrooxidation of the related naturally occurring polycyclic methylcyclopropanes, cyclofenchene (1b) and longicyclene (1c), followed by hydrolysis also brought about stereo- and regioselective cleavage of carbon-carbon bonds of the cyclopropane rings to give the corresponding homoallylic alcohols 2b,c in good yields.

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