466-12-6

Basic information

• Product Name: Bicyclo[2.2.1]heptane-2-methanol, 2-hydroxy-3,3-dimethyl-
• CAS NO: 466-12-6
• Molecular Formula: C10H18O2
• Molecular Weight: 170.252
• Mol File: 466-12-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Bicyclo[2.2.1]heptane-2-methanol, 2-hydroxy-3,3-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Bicyclo[2.2.1]heptane-2-methanol, 2-hydroxy-3,3-dimethyl-(466-12-6)
• EPA Substance Registry System: Bicyclo[2.2.1]heptane-2-methanol, 2-hydroxy-3,3-dimethyl-(466-12-6)

Safety Data

• Hazardous Substances Data: 466-12-6(Hazardous Substances Data)

Upstream product

• 79-92-5 camphene 
• 7732-18-5 water 
• 71-43-2 benzene 
• 79-21-0 peracetic acid 
• 565-00-4 dl-camphene 
• 7722-84-1 dihydrogen peroxide 
• 64-19-7 acetic acid 

Downstream Products

• 472-17-3 (1S,4R)-3,3-Dimethyl-bicyclo[2.2.1]heptane-2-carbaldehyde 
• 13211-15-9 (+-)-camphenilone 
• 81374-87-0 2-hydroxycamphenilic acid 
• 473-35-8 2-(3-carboxy-cyclopentyl)-2-methyl-propionic acid 
• 50705-16-3 3,3-dimethylbicyclo[2.2.1]heptane-2-carbaldehyde 

Relevant articles and documents

CLXXV. - Contributions to the chemistry of the terpenes. Part IX. The oxidation of camphene with hydrogen peroxide

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Electrochemical Oxidation of Polycyclic Cyclopropanes and Camphene. Novel Synthesis of exo-5,5-Dimethyl-6-methylenebicycloheptan-2-ol (Nojigiku Alcohol)

Anodic oxidation of tricyclene (1a) in acetic acid containing triethylamine, followed by hydrolysis, provides a facile and efficient synthesis of exo-5,5-dimethyl-6-methylenebicycloheptan-2-ol (2a), named "nojigiku alcohol", which was isolated from the essential oil of chrysanthemum japonese.Furthermore, a method for large-scale production of 2a starting from the readily available impure starting tricyclene (1a) has been developed by appropriate selection of reaction conditions.Similar electrooxidation of the related naturally occurring polycyclic methylcyclopropanes, cyclofenchene (1b) and longicyclene (1c), followed by hydrolysis also brought about stereo- and regioselective cleavage of carbon-carbon bonds of the cyclopropane rings to give the corresponding homoallylic alcohols 2b,c in good yields.