79-92-5 Usage
Chemical Properties
Different sources of media describe the Chemical Properties of 79-92-5 differently. You can refer to the following data:
1. WHITE CRYSTALLINE LOW MELTING SOLID
2. Camphene has a terpene, camphoraceous taste.
Occurrence
Reported found in carrot, dill, fennel, marjoram, nutmeg, parsley, pepper, tarragon and thyme.
Uses
Different sources of media describe the Uses of 79-92-5 differently. You can refer to the following data:
1. Camphene is used in the preparation of fragrances and as a food additive for flavoring.
2. Manufacture of synthetic camphor, camphor
substitute.
Definition
ChEBI: A monoterpene with a bicyclic skeleton that is bicyclo[2.2.1]heptane substituted by geminal methyl groups at position 2 and a methylidene group at position 3. It is a widespread natural product found in many essential oils.
Preparation
From pinene by catalytic isomerization or from bornyl chloride by heating with alkali in the presence of abietenesulfonic acid.
Aroma threshold values
Detection at 10%: camphoraceous, cooling, piney woody with terphy nuances. It has citrus and green
minty and green spicy notes.
Taste threshold values
Taste characteristics at 50–100 ppm: camphoraceous, cooling, minty, with citrus and green spicy nuances.
General Description
A colorless to white crystalline solid with an insipid camphor-like odor. Dust and crystals are irritants to the eyes, nose and throat. Emits flammable vapors when heated. Emits acrid smoke and irritating fumes at high temperature. Used for the manufacture of synthetic camphor.
Reactivity Profile
Camphene may react vigorously with strong oxidizing agents. May react exothermically with reducing agents to release hydrogen gas.
Hazard
Toxic by ingestion.
Flammability and Explosibility
Flammable
Pharmacology
Oral administration of camphene (260 mmols/kg) to rats increased bile flow by 50%
4 hr after administration (M?rsdorf, 1966). Development of atheromatosis of the aorta in rabbits
fed 1 g cholesterol/day for 3 months was considerably inhibited by simultaneous administration
of a mixture of terpenes including camphene, injected sc in a dose of 1 ml every other day for
6 wk and then given orally in doses of 2 ml/day (Benk?, Macher, Szarvas & Tiboldi, 1961). The
effect of 1 g cholesterol/day for 8 wk in the diet of rabbits in increasing the number and volume
of mast cells in the aortic adventitia and increasing the total lipid content of the aortic wall was
slightly enhanced by the simultaneous addition of 11 g camphene/day (Lesznyak, Benko, Szabo
& Muller, 1972). This camphene treatment also decreased the lipid accumulation in the liver, but
had no effect on the cholesterol-induced atheromatosis of the aorta (Benko, Szabo, Muller & Lesznyak,
1972).
Anticancer Research
This was tested against melanoma cells in a syngeneic model, and there was promisingantitumor activity (Ma et al. 2016).
Safety Profile
Mutation data reported.
Combustible; yields flammable vapors when
heated and can react with oxidizing
materials. To fight fire, use water spray,
foam, fog, CO2. When heated to
decomposition it emits acrid smoke and
irritating fumes.
Waste Disposal
Dissolve or mix the material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal,
state, and local environmental regulations must be
observed.
Check Digit Verification of cas no
The CAS Registry Mumber 79-92-5 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 7 and 9 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 79-92:
(4*7)+(3*9)+(2*9)+(1*2)=75
75 % 10 = 5
So 79-92-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H16/c1-7-8-4-5-9(6-8)10(7,2)3/h8-9H,1,4-6H2,2-3H3
79-92-5Relevant articles and documents
Lockhart
, p. 219,224 (1974)
Highly-selective solvent-free catalytic isomerization of α-pinene to camphene over reusable titanate nanotubes
Huang, Geng,Liu, Jian,Su, Shengpei,Yin, Dulin,Zhou, Shuolin
, p. 10606 - 10611 (2020)
Titanate nanotubes, prepared by the hydrothermal reconstitution and modification with hydrochloric acid, were tested as solid acid catalysts in the isomerization of α-pinene under solvent free conditions. The results showed that titanate nanotubes have be
-
Wolinsky,J.,Eustace,E.J.
, p. 3654 - 3658 (1975)
-
Discovering Monoterpene Catalysis Inside Nanocapsules with Multiscale Modeling and Experiments
Pahima, Efrat,Zhang, Qi,Tiefenbacher, Konrad,Major, Dan T.
, p. 6234 - 6246 (2019/04/25)
Large-scale production of natural products, such as terpenes, presents a significant scientific and technological challenge. One promising approach to tackle this problem is chemical synthesis inside nanocapsules, although enzyme-like control of such chemistry has not yet been achieved. In order to better understand the complex chemistry inside nanocapsules, we design a multiscale nanoreactor simulation approach. The nanoreactor simulation protocol consists of hybrid quantum mechanics-molecular mechanics-based high temperature Langevin molecular dynamics simulations. Using this approach we model the tail-to-head formation of monoterpenes inside a resorcin[4]arene-based capsule (capsule I). We provide a rationale for the experimentally observed kinetics of monoterpene product formation and product distribution using capsule I, and we explain why additional stable monoterpenes, like camphene, are not observed. On the basis of the in-capsule I simulations, and mechanistic insights, we propose that feeding the capsule with pinene can yield camphene, and this proposal is verified experimentally. This suggests that the capsule may direct the dynamic reaction cascades by virtue of π-cation interactions.
Wijayati,Handayani,Supartono
, p. 1705 - 1708 (2017/06/27)
